
This week in medicine
A new obesity target, a better way to discover new cancer drug targets, pyroptosis inhibitors for sepsis, an orexin agonist for narcolepsy, and more.
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A new obesity target, a better way to discover new cancer drug targets, pyroptosis inhibitors for sepsis, an orexin agonist for narcolepsy, and more.

A hit to the inflammation theory of cardiovascular disease, a non-opioid painkiller, progress for vitiligo, and more.

Finding cancer drug targets with Codex

Age-related atrophy is a growing problem, but there are no biomarkers, no medicines, the trials aren’t working and the data aren’t good enough.

Welcome!

... and the companies that'll build it

Welcome!

We’re 6 months into 2026, so what better time for a rundown of what’s happened so far?
A podcast episode

Welcome! Every week I analyze the 5 most important things that happened in the world of medicine... let’s get into it!

I spent the last week in beautiful Chicago at the biggest cancer conference in the world (ASCO: the American Society of Clinical Oncology).

Welcome!

A story on the limits of current immunotherapy in cancer, new developments and pivoting cancer treatments to other diseases, highlighting a great publication on idiopathic pulmonary fibrosis

Welcome!

Welcome!

It was a busy week in biomedicine, it is difficult to keep up!

5 breakthroughs in medicine this week

... and factor XI inhibitors, and HER2 inhibitors

Progress in medicine is fast!

I love a16z’s Charts of the Week series, so I have shamelessly stolen the idea.