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Breakthrough

Keep up to date with the cutting edge of medicine.

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This week in medicine

A new obesity target, a better way to discover new cancer drug targets, pyroptosis inhibitors for sepsis, an orexin agonist for narcolepsy, and more.

This week in medicine

A hit to the inflammation theory of cardiovascular disease, a non-opioid painkiller, progress for vitiligo, and more.

Can AI discover new science?

Finding cancer drug targets with Codex

Entelo Bio CEO, Peter Crane, on preserving human resilience

Age-related atrophy is a growing problem, but there are no biomarkers, no medicines, the trials aren’t working and the data aren’t good enough.

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This week in medicine: towards cure for type 1 diabetes, a new cholesterol drug, anti-aging progress, and more.

Welcome!

Predictions for the future of medicine

... and the companies that'll build it

This week in medicine: preventing pancreatitis, a new dementia drug target, and more.

Welcome!

10 breakthroughs in biomedicine in 2026... so far

We’re 6 months into 2026, so what better time for a rundown of what’s happened so far?

New cancer breakthroughs, China vs. USA in biotech, and the future of cancer therapy

A podcast episode

This week in medicine: more pancreatic cancer progress, a best-in-class ulcerative colitis drug, and more

Welcome! Every week I analyze the 5 most important things that happened in the world of medicine... let’s get into it!

5 highlights from the biggest cancer conference in the world

I spent the last week in beautiful Chicago at the biggest cancer conference in the world (ASCO: the American Society of Clinical Oncology).

This week in medicine: new drug classes, and progress for disease prevention

Welcome!

NK-cell immunotherapy was developed for oncology, but may take off elsewhere

A story on the limits of current immunotherapy in cancer, new developments and pivoting cancer treatments to other diseases, highlighting a great publication on idiopathic pulmonary fibrosis

This week in medicine: guided cancer therapy, a new Alzheimer's trial, and more

Welcome!

Progress in medicine this week: a breakthrough cardiac drug, a new cancer drug, and more...

Welcome!

Progress in medicine this week: GLP1s for addiction; fixing hair loss; and more

It was a busy week in biomedicine, it is difficult to keep up!

This week's medical progress (including the first gene therapy for genetic hearing loss)

5 breakthroughs in medicine this week

A breakthrough week for KRAS inhibitors

... and factor XI inhibitors, and HER2 inhibitors

Medical breakthroughs this week (including a better, potentially curative, sickle cell therapy)

Progress in medicine is fast!

Charts of the week: multiple myeloma progress, predicting clinical trials with AI, and GLP1s eating the world

I love a16z’s Charts of the Week series, so I have shamelessly stolen the idea.