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Mind & Matter

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers about how your mind-body reacts to what it's fed. New content weekly. Not medical advice.

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Non-Prescription Substances to Lower Arterial Plaque

Nutrients & supplements that can help with arterial plaque, and the intriguing biology they share in common.

GDF15: Health & Aging Biomarker Everyone is Missing?

GDF15 is a remarkable stress-induced biomarker of energy resistance and health.

Watching the Watchers: Consumer Product Lab Testing & Its Discontents

Third-party lab testing can be corrupt. In a world filled with fraud and fakery, research, risk tolerance, and self-experimentation may be necessary.

Human Genetic Variation in Mitochondrial Peptides, Metabolism & Longevity

Natural genetic variants in mitochondrial peptides are linked to health benefits... and risks.

Mitochondria Peptides: MOTS-c, Humanin, Genetic Variation in Health & Disease | Pinchas Cohen | Episode 304

Mitochondrial DNA encodes functional microproteins once dismissed as junk. A humanin variant enriched in centenarians appears to neutralize APOE4 cognitive risk.

Neuro-Immune Interactions: Pain, Inflammation, Peptides & Healing | Isaac Chiu | Episode 303

How the nervous and immune systems communicate, using peptides and other signals, to regulate pain, itch, and inflammation.

Metabolic Stress & the Peptide MOTS-c: How Much is Too Much?

The MOTS-c peptide has powerful effects on metabolism, but too much may come with series risk. Potency and dosing schedule will be critical.

MOTS-c & Mitochondrial Peptides in Health & Aging | David Lee | Episode 302

Mitochondrial peptide MOTS-c is a stress-induced signal that reprograms cell metabolism.

Copper Peptides, Skin Health & Oxidative Stress

Copper peptides like GHK-Cu have remarkable effects on oxidative stress and inflammation, in the skin and beyond.

Peptides & GHK-Copper in Skin Health | Rahi Sarbaziha | Episode 301

GHK-Copper and peptides in skin care, aging, and general health.