# Mind & Matter

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers about how your mind-body reacts to what it's fed. New content weekly. Not medical advice.

Page: <https://rssamplifier.com/mindandmatter-substack-com>  
Feed: <https://rssamplifier.com/mindandmatter-substack-com.md>

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## [Non-Prescription Substances to Lower Arterial Plaque](https://mindandmatter.substack.com/p/non-prescription-substances-to-lower)

_2026-08-18 · Nick Jikomes, PhD_

Nutrients & supplements that can help with arterial plaque, and the intriguing biology they share in common.

## [GDF15: Health & Aging Biomarker Everyone is Missing?](https://mindandmatter.substack.com/p/gdf15-health-and-aging-biomarker)

_2026-08-14 · Nick Jikomes, PhD_

GDF15 is a remarkable stress-induced biomarker of energy resistance and health.

## [Watching the Watchers: Consumer Product Lab Testing & Its Discontents](https://mindandmatter.substack.com/p/watching-the-watchers-consumer-product)

_2026-08-11 · Nick Jikomes, PhD_

Third-party lab testing can be corrupt. In a world filled with fraud and fakery, research, risk tolerance, and self-experimentation may be necessary.

## [Human Genetic Variation in Mitochondrial Peptides, Metabolism & Longevity](https://mindandmatter.substack.com/p/human-genetic-variation-in-mitochondrial)

_2026-08-07 · Nick Jikomes, PhD_

Natural genetic variants in mitochondrial peptides are linked to health benefits... and risks.

## [Mitochondria Peptides: MOTS-c, Humanin, Genetic Variation in Health & Disease | Pinchas Cohen | Episode 304](https://mindandmatter.substack.com/p/mitochondria-peptides-mots-c-humanin)

_2026-08-04 · Nick Jikomes, PhD_

Mitochondrial DNA encodes functional microproteins once dismissed as junk. A humanin variant enriched in centenarians appears to neutralize APOE4 cognitive risk.

## [Neuro-Immune Interactions: Pain, Inflammation, Peptides & Healing | Isaac Chiu | Episode 303](https://mindandmatter.substack.com/p/neuro-immune-interactions-pain-inflammation)

_2026-08-03 · Nick Jikomes, PhD_

How the nervous and immune systems communicate, using peptides and other signals, to regulate pain, itch, and inflammation.

## [Metabolic Stress & the Peptide MOTS-c: How Much is Too Much?](https://mindandmatter.substack.com/p/metabolic-stress-and-mots-c-how-much)

_2026-08-01 · Nick Jikomes, PhD_

The MOTS-c peptide has powerful effects on metabolism, but too much may come with series risk. Potency and dosing schedule will be critical.

## [MOTS-c & Mitochondrial Peptides in Health & Aging | David Lee | Episode 302](https://mindandmatter.substack.com/p/mots-c-and-mitochondrial-peptides)

_2026-07-30 · Nick Jikomes, PhD_

Mitochondrial peptide MOTS-c is a stress-induced signal that reprograms cell metabolism.

## [Copper Peptides, Skin Health & Oxidative Stress](https://mindandmatter.substack.com/p/copper-peptides-skin-health-and-oxidative)

_2026-07-18 · Nick Jikomes, PhD_

Copper peptides like GHK-Cu have remarkable effects on oxidative stress and inflammation, in the skin and beyond.

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## [Peptides & GHK-Copper in Skin Health | Rahi Sarbaziha | Episode 301](https://mindandmatter.substack.com/p/peptides-and-ghk-copper-in-skin-health)

_2026-07-17 · Nick Jikomes, PhD_

GHK-Copper and peptides in skin care, aging, and general health.