Tales from the Wards 2.0
Six real cases. Could AI Have helped?
A&Ox2
Reorienting the conversation in medicine and health care
Live Last read · last published · next check
Latest episodes
It's So Hard...
If you grew up in the 1990s, is your brain already singing the next line?A&Ox2 is a reader-supported publication.
Can Autonomous Vehicles Save Lives?
From Waymo's safety data to the launch of our AVERT Study
Reflections on the Retraction of the Time-of-day Immunotherapy Trial
Profound Sadness for the State of Science
Metformin for Prediabetes: Treating the Label, Not the Patient
Prediabetes is useful as a risk marker. It is a signal to take metabolic health seriously. But metformin for prediabetes is a different claim. It says that changing the timing of a diagnosis is itself enough to justify medication. That is where the logic breaks.
Tales from the Wards 1.0
A potpourri of clinical pearls from my practice
Flawed Research is Not Hypothesis Generating
An Example of Thickened Fluids in Dementia
'Learners' or 'Doctors'?
Rethinking language and responsibility in medical training
Hyponatremia: Does Correcting it Help?
Hyponatremia reliably predicts bad outcomes. But does correcting it fix them? A new randomized trial makes that uncomfortable truth harder to ignore.
If Jesus Practiced Medicine Today, He'd Only Generate 68.27 wRVUs
A satirical commentary on valuing what is easiest to measure, not what matters most
Resmetirom: a new drug that is already outclassed
Why doctors should abandon the new shiny drug for MASH in favor of a far superior drug class.
Conferencing is Better in the Public Square
If the goal in academia is exchange, networking, and collaborations, then we should stop pretending the hotel ballroom is the only or even the best way to achieve that.
It Is Time for Hospitalists to Own Our Expertise
Defining the expertise at the heart of hospital medicine
Wolf in Academic’s Clothes
The Message of Eric Topol’s Peter Attia Takedown
How Good is Your Doctor? Medicine Doesn’t Know
We recognize great doctors when we see them, but our systems measure the wrong things
Guidelines Schmidelines Part 2
The humility of uncertainty & WikiGuidelines by Dr. Spellberg
Guidelines Schmidelines Part 1
Watch now | Why Following Guidelines is Not Synonymous with EBM
Why Shorter is Better for Antibiotics
Watch Dr. Spellberg now | UCSF Division of Hospital Medicine Grand Rounds at San Francisco General Hospital
Retract Until Verified
The Implausibly Large Effect in the Recent Time-of-Day Immunotherapy Trial
Uproar Over Moderna’s Flu Vaccine Cancellation. Crickets Over Evidence.
What Moderna's data tell us about the efficacy of their mRNA vaccine