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Uncertainty Principles

When what we don’t know is more important than what we do. Wrestling with conflict and controversy in science, medicine, health and nutrition.

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Blah Health Journalism: Meat, Sauerkraut and Politics Edition.

What's it take to get the traditional media (or at least The New York Times) to understand the appeal of unconventional diets?

Karl-Anthony Towns, Food Noise, and Why GLP-1 Drugs Quiet the Brain

The Liver?! What's the liver got to do with it?

Shouldn’t Giving Birth Be (Reasonably) Easy?

The Obstetrical Dilemma. What really makes human childbirth so hard?

"Bad Air" or the Tobacco Industry Playbook?

Which is the better metaphor for the controversy over ultra-processed foods?

"The dead end of the energetics view"

I spoke at NIH on Friday describing how pre-WW2 medical scientists dismissed the simplistic notion that we get fat because we eat too much.

Shouldn't Where We Get Fat (and When) Tell Us Something About Why?

More observations from the history of a very bad idea.

Diet or Drugs, Calories or Carbohydrates? Longevity medicine comes for your dog.

Beneath the headlines, the carbohydrate-insulin model is now hiding in plain sight.

The History of a Very Bad Idea: Understanding Obesity Before Calories In and Out.

How would you discuss the cause of obesity if you weren't burdened by the notion that it's an energy balance disorder?

Brain Health vs. Heart Health? Is Eating Meat Good for Cognition but Bad for Our Arteries?

A new Swedish study on meat consumption and Alzheimer's Disease speaks to the "anti-randomization" problem of nutrition science.

The "One of Us Stinks" Problem: LDL, the Lipid Hypothesis, the AHA, and Humphrey Bogart

Wouldn't it be nice to think that arguments and evidence can change minds? I wouldn't bet on it.