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Hans' Substack

The frontline of male physiology. I run the experiments no one else will and turn the data into systems that build elite hormones and performance. Follow if you want to stay ahead of every man you know.

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I mega-dosed methylene blue. Here’s what happened

I wanted to see what methylene blue would do to my estrogen, mitochondria, NADH/NAD recycling, ATP production, and serotonin, as well as whether there would be any serendipitous discoveries along the way.

Complete NAD maxxing guide (everything you need to know about NAD)

NAD+ Isn’t One Thing.

What Everyone Gets Wrong About Estrogen Management

My testosterone is >3500 ng/dL and my estradiol sits around 100-120 pg/mL, and I run zero milligrams of an aromatase inhibitor.

Does PEA really increase DHT

I ran 4 hormone panels to find out. The results didn't match the one study everyone keeps citing.

Why You're Not Making Progress

A short history of every health trend you’ve tried (and the real reason none of them stuck)

How To Take Pregnenolone For Mood, Relaxation, Focus and Hormonal Support

Pregnenolone is probably the most important hormone we have.

Wrong Diagnosis, Right Symptoms: Why He Never Had PFS

A client came to me convinced he had post-finasteride syndrome.

The Acne Root Cause Protocol: Why Your Gut Is Behind Your Breakouts

Acne Is Not a Skin Problem.

How To Lower Gut Inflammation

Without having to rely on 100s of supplements

The Great Fiber Lie: What Beans Actually Do to Your Microbiome

To fiber or not to fiber, that’s the question.

Everything You Need to Know About Cortisol Testing

And how to lower/manage cortisol

Mega-Dosing Thymoquinone Broke My Energy Metabolism

“Support your mitochondria.”

I Megadosed Creatine at 45g/Day. Here's What It Did to My Hormones.

Creatine is the most viral and hyped supplement of all time.