The Human Proteome Was Never Finished
Scientists mapped HLA peptide evidence to 1,785 overlooked reading frames. The signal is real. Whether they are proteins remains unsettled.
The Peptide List
Independent peptide intelligence: clinical evidence, provider and lab scrutiny, regulatory shifts, and the genetics research behind why response varies.
Live Last read · last published · next check
Latest posts
Scientists Built a Peptide That Tags Alzheimer’s Amyloid for Destruction
In mice, SPYTAC crossed the blood–brain barrier, recruited LRP1, and sent amyloid to lysosomes. Human clinical evidence is absent
The Immune System Learned to Attack Gluten. Scientists Are Trying to Teach It to Stop.
A roughly 20-nanometer particle platform carries 12 gluten peptides and rapamycin into a first-in-human trial. The first signal is real. Clinical tolerance is not.
Nobody Built an Exit From Ozempic
Patients stop. Coverage ends. Treatment restarts. The drugs have a maintenance plan. The care system has no tested transition.
Enclomiphene Lost Every Vote It Ever Faced. That Is Why You Can Buy It.
Four regulators said no. The FDA never wrote the rule. A public company now bills a subscription against the gap.
Nobody Was Asking Anymore. The FDA Voted Anyway.
Fourteen times the agency’s scientists said no. The panel overruled them twelve times, and killed the one peptide with real evidence.
SS-31 Was an Anti-Aging Peptide. Now It’s a Barth-Syndrome Drug.
Open two browser tabs.
GLP-1s Are Organ Drugs Now. Weight Loss Is the Side Effect.
Heart, kidney, liver, airway: the label quietly turned a weight shot into organ medicine. The brain is where it stopped.
Why Mounjaro Makes You Vomit and Ozempic Doesn’t. It’s Your GIPR Gene.
One gene, one receptor, and the reason two drugs in the same class treat your gut in completely different ways.
The FDA’s Own Scientists Said No. The Panel That Decides Sells Peptides.
Days before the vote, the FDA’s own reviewers came out against the seven peptides. The panel that decides is full of people who sell them.