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Polypharmacy

Rationalist-adjacent musings on psychiatry

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Seems Like Psychiatrists Should Probably Know About Modern Personality Theory: Part 2

Welcome to Part 2 in a series about the history of modern personality theory, with an emphasis on the Five Factor Model.

The FDA's approval of Auvelity for agitation in dementia: An appraisal

About the recent FDA approval of Auvelity in agitation associated with Alzheimer’s dementia

We should stop running psychiatric clinical trials that cannot change practice

The case of prazosin for PTSD nightmares and the PACT trial

One Year of Being An Attending

It's pretty good, actually

Should we prescribe antidepressants like statins?

Making sense of the placebo response in antidepressant clinical trials

Seems Like Psychiatrists Should Probably Know About Modern Personality Theory: Part 1

Galton, Alport and Odbert Make A List, and Cattell Makes A Smaller One

The new "chemical imbalance" myth for depression

Does TMS correct “underactive" brain regions that cause depression, or are we repeating mistakes of the past?

Same As It Ever Was

No Surprises In The 52-Week Open-label Cobenfy Study

Should All Depressed Patients Be On Adjunctive Mirtazapine?

Explaining heterogeneity, tau, and random-effects models to better understand the meaning of a major meta-analysis

Yes, Involuntary Commitment Really Is That Complicated

I do not even have a mustache to twirl