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Neurobiology Notes

When blogging about brain preservation, it's publish or perish

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The wrong Gustav Mann

On the independent invention of perfusion fixation in neuroscience

Action Potentials for July

1: Expansion microscopy, first developed only a bit over a decade ago (shameless nerd bragging alert, I wrote the Wikipedia entry on it in October 2015), has now exploded.

Action Potentials for June

1: Like all animals, young C. elegans nematodes need food to grow and reproduce.

It seems easier to simulate a nervous system than a cell

The complexity of cellular reactions is at once both daunting and awe-inspiring.

Action Potentials for May

1: Synapses are clearly important aspects of the brain, but they obviously aren’t the only thing.

Action Potentials for April

1: One of my supervisors in psychiatry residency would explain concepts to patients by using the analogy of the brain as a computer.

Action Potentials for March

1: Now that we are getting increasingly good at generating connectomes, if we only got better at neuron typing, we could theoretically test Sebastian Seung’s vision of simulating neuronal information flow via connectomes and cell types.

Action Potentials for February

1: A new GWAS of schizophrenia is notable for including a substantial number of people of African ancestry, with 13.5K such cases and 65K controls.

Honey, I shrunk the brain

When cryoprotectants are perfused through the blood vessels in the brain, they cannot cross the blood-brain barrier as fast as water can move in the opposite direction.

Action Potentials for January

1: A connectome is a static snapshot of the microstructure of the brain.