
The wrong Gustav Mann
On the independent invention of perfusion fixation in neuroscience
When blogging about brain preservation, it's publish or perish
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On the independent invention of perfusion fixation in neuroscience

1: Expansion microscopy, first developed only a bit over a decade ago (shameless nerd bragging alert, I wrote the Wikipedia entry on it in October 2015), has now exploded.

1: Like all animals, young C. elegans nematodes need food to grow and reproduce.

The complexity of cellular reactions is at once both daunting and awe-inspiring.

1: Synapses are clearly important aspects of the brain, but they obviously aren’t the only thing.

1: One of my supervisors in psychiatry residency would explain concepts to patients by using the analogy of the brain as a computer.

1: Now that we are getting increasingly good at generating connectomes, if we only got better at neuron typing, we could theoretically test Sebastian Seung’s vision of simulating neuronal information flow via connectomes and cell types.

1: A new GWAS of schizophrenia is notable for including a substantial number of people of African ancestry, with 13.5K such cases and 65K controls.

When cryoprotectants are perfused through the blood vessels in the brain, they cannot cross the blood-brain barrier as fast as water can move in the opposite direction.

1: A connectome is a static snapshot of the microstructure of the brain.