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Brain Inflammation Collab

Insights into the inflammatory mechanisms linking infection-associated chronic conditions with their overlapping comorbidities. Written by a former Ph.D. biomedical researcher | All paid subscriptions are donations that support our research.

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Inflammation Biosensors

How a molecular-pendulum biosensor is opening the door to continuous tracking of key cytokines, and what it could mean for chronic inflammatory diseases.

What If Some Pediatric Mental Health Symptoms Are Driven by Inflammation?

As rates of anxiety and depression rise among children and adolescents, emerging evidence points to neuroinflammation as a potentially overlooked factor—particularly in treatment-resistant and post-in

Unhiding the Bigger Picture of Ehlers-Danlos Syndrome

New preliminary data from unhide® shows how EDS overlaps with other complex chronic conditions—and what patients experience beyond a single diagnosis.

Can Carbon Dioxide Help the Brain Clear Toxic Proteins?

A new study suggests brief bursts of inhaled CO₂ may enhance the brain's waste-clearing system, offering a potential new approach for Parkinson's and Alzheimer's disease.

Autoimmune Dementia

How autoantibodies can attack the brain to cause dementia, the red flags doctors look for, and why early immunotherapy can reverse symptoms.

Long COVID and ME/CFS Are Not Just Deconditioning

A new study found that post-exertional malaise causes distinct muscle abnormalities that cannot be explained by simply being "out of shape."

Revisiting: Long COVID Research Updates and Hispanic Community Impact

Exploring the latest science on Long COVID while expanding access to research for Spanish-speaking communities

When “Psychosis” Is Really an Autoimmune Attack on the Brain

How PhIP-Seq is Helping Researchers Find Brain-Attacking Autoantibodies Previously Unknown to Science

Revisiting: Untangling Brain Fog with Neuroscientist Mara Kuvaldina, Ph.D.

Why studying brain fog across multiple conditions may help us better understand one of the most common and debilitating symptoms of neuroinflammation.

She Spent 20 Years in a Psychiatric Hospital. Then She Woke Up.

She Spent 20 Years in a Psychiatric Hospital. Then She Woke Up.

She Was Told It Was Depression. It Was Her Immune System Attacking Her Brain.

A psychiatrist spent six years searching for answers before discovering brain-targeting autoantibodies and recovering with immunotherapy.

Inflammation in the Body and Depression in the Brain

Can Chronic Inflammation in the Body Cause Mental Health Complications? A Brief History and Current Evidence.

Revisiting: IVIG Access for PANS

Our latest research confirms what many families have experienced: accessing IVIG can be one of the greatest challenges in PANS care.

New Lupus Research Highlights the Power of the Gut Microbiome

Restoring a beneficial gut bacterium corrected metabolic abnormalities and reduced autoimmune disease markers in lupus-prone mice.

Wildfire Smoke Is More Than an Air Quality Problem

Tiny airborne particles can trigger inflammation throughout the body, potentially worsening fatigue, brain fog, headaches, and other symptoms in vulnerable individuals.

Could the Second X Chromosome Help Explain Why Autoimmune Diseases Disproportionately Affect Women?

New research suggests chronic inflammation may disrupt X chromosome silencing in immune cells, offering a potential biological explanation for why women develop autoimmune diseases at much higher rate

Why Long COVID Steals Motivation and Mental Clarity: A Dopamine Discovery

Researchers used advanced PET scans to uncover what may explain the crushing fatigue, apathy, and cognitive issues that won’t go away.

Revisiting: Insights into Mood and Mind in Infection-Associated Chronic Conditions

What shared symptoms across PANS/PANDAS, Long COVID, ME/CFS, and chronic Lyme disease can teach us about brain inflammation.

Could the Brain's "Waste Disposal" System Play a Role in ME/CFS?

A new preliminary study links impaired glymphatic function to brain fog and sleep problems in people with ME/CFS.

The Blood’s Tiny Black Boxes: What Microclots Reveal About Long COVID and POTS

Microclots Trap Soluble Molecules In The Blood, Providing Insight Into The Pathological Features of Long COVID and POTS