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Alex's Substack

Thoughts on science, impact, and lasting, positive social change.

alexaraki.substack.comSource feed ↗20 episodes

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The Race to Allocate One Trillion Dollars in Philanthropic Capital

Frontier Lab IPOs are coming, and philanthropy isn’t ready

Ten more unintuitive things about impact philanthropy fundraising

some more lessons I’ve learned, for the $free.99

Links #11

it's sunny in London

19 things I've learned

from one year of "unemployment"

The disease we keep calling a symptom

The framing problem of chronic pain

The world needs more seed stage philanthropy

How to give your money away, better than anyone else

The Sotheby's Theory of Impact Philanthropy

Curation or investing?

"Where's the gold?" — A Gene Therapist's Tale of Cell and Gene Therapy

circa 2018–2025

the entire universe is rooting for you

inflections from Kevin Kelly’s words

Why We Still Don't Have Continuous Hormone Monitors

Monitoring the Human Operating System

We Keep Discovering Biomarkers. We Keep Failing to Build Them.

What’s stopping us isn’t (just) the science.

People never follow up

Thoughts on bending entropy

Links #10

A great piece by Leah Sargeant in Asterisk Magazine on the elite filtering system of high school science fairs. As a kid who did these fairs, hard agree.

Where are all the biomarkers for chronic pain?

Current techniques for "objective" measures of chronic pain

How to feel invisible

My journey with chronic pain

Links #9

It's way too cold in NY

What if you just did a startup instead?

A pro-startup, pro-metascience hit piece

How will I measure my life?

Inspired by: "How will you measure your life?" by Clayton Christensen

Links #8

moar links, moar links

Philanthropists aren’t on LinkedIn

Advice for navigating impact philanthropy fundraising