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Lucy James is Sherlock Holmes's original investigative partner in Charles Veley's historical mystery novels and short stories.

Lisette Darling investigates murder in Colette Clark's historical mystery series set among 1920s Hollywood's studios and social circles.

Lady Eleanor Swift is the amateur detective in Verity Bright's 1920s historical mystery series, investigating cases with her butler, Clifford.

Lucy Clayburn is the undercover police officer at the center of Paul Finch's connected crime-thriller trilogy.

Locke Lamora is the thief and con artist leading Scott Lynch's Gentleman Bastards through elaborate schemes in the fantasy city of Camorr.

Lyra Belacqua is the young protagonist of Philip Pullman's His Dark Materials, beginning her journey in an alternate Oxford with her daemon Pantalaimon.

Lexie Maxwell is Amy Maxwell's daughter and the young detective in Heather Balog's three-book Lexie Maxwell Diaries, a middle-grade mystery spin-off.

Lizzie Turner is the amateur sleuth in Linda Wiken's Ashton Corners Book Club Mysteries, written as Erika Chase and set in small-town Alabama.

Lord Edgington is the retired police superintendent in Benedict Brown's 1920s historical mysteries, investigating murders with his grandson Christopher.

Laura Foster is the police detective in Amy Cross's three-book crime horror series, where investigations move beyond ordinary explanation.

Detective Lew Kirby leads S.W. Kane's English crime series, investigating cases in isolated communities and troubled institutions.

Laurel McKay is the divorced mother and bank loan officer who becomes an amateur detective in Cindy Sample's cozy California mysteries.

Lara Croft is the archaeologist-adventurer featured in James Alan Gardner's Tomb Raider tie-in novels.

Long Wu Ying is the farmer's son at the center of Tao Wong's A Thousand Li, a cultivation fantasy series about sect training, spiritual advancement, and its costs.

DI Lexi Bennett leads major investigations in Alison Belsham's Canterbury crime trilogy, where profiling work intersects with a family trauma.

Lexie Carrigan is the teenage lead of S. Usher Evans' Lexie Carrigan Chronicles, a young adult fantasy series about inherited warrior magic in small-town Florida.

Lillie Dean is the magical baker at the center of S. Usher Evans' Pobyd Perfections Bakery, a cozy fantasy mystery series set in Silverkeep.

Dr. Lyssa Peate is the scientist and secret bounty hunter at the center of S. Usher Evans's Razia space opera series.

Libertus is the Celtic freedman and mosaic maker who investigates crimes in Rosemary Rowe's historical mysteries set in Roman Britain.

Lydia Crow is a London private investigator whose cases bring her into the power struggles of four magical families in Sarah Painter's urban fantasy series.

Lisbeth Salander is the hacker at the center of the Millennium crime novels, where she works with journalist Mikael Blomkvist on investigations into Swedish power and abuse.

Lincoln Rhyme is Jeffery Deaver's quadriplegic forensic detective, who works with NYPD detective Amelia Sachs on complex crime investigations.

Lily Goode is the witch at the center of Michelle M. Pillow's (Un)Lucky Valley, a cozy paranormal mystery series set in Colorado.

Lestat de Lioncourt is a central vampire in Anne Rice's Vampire Chronicles, appearing across the series' long history of immortal characters.