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COVID-19 Research

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Could Macrophages Be the Trojan Horses of Persistent SARS-CoV-2?

A new preprint may provide an important piece of the puzzle for what I have been calling Smoldering Macrophage Syndrome.

Friday Hope: Panax notoginseng — A Botanical Ally for the Endothelium that May Actually Reverse SPED Damage

Panax notoginseng may also treat acute COVID by inhibiting the “cytokine storm.”

HLA-DRB1 Alleles: Could Our Immune Genetics Help Explain the Many Faces of Long COVID?

One of the most striking features of Long COVID, and one that I have been seeking to understand from the beginning, is its heterogeneity. We may now have an answer.

Friday Hope: Hibiscus: An Ancient Remedy with Modern Promise Against SARS-CoV-2 and Endothelial Injury

For thousands of years, Hibiscus sabdariffa—known as roselle—has been consumed as both a refreshing beverage and a medicinal herb.

Smoldering Macrophage Syndrome, the Spike Protein and Sudden Cardiac Death: A New Mechanistic Hypothesis

I propose the loss of cardiac resident macrophages induced by the Spike Protein may contribute to the dramatic increase in sudden cardiac death in unexpected populations.

Friday Hope: Andrographolide: Attacking Smoldering Macrophage Syndrome from Both Directions

This “King of Bitters” appears to target both viral stimulus and downstream macrophage dysfunction.

From Macrophage Activation Syndrome (MAS) to "Smoldering Macrophage Syndrome (SMS)"—Is the Spike Protein Keeping the Fire Burning?

It’s all about levels of activation, and the Spike likes to keep it at a simmer.

Friday Hope: Resveratrol and FcγRIIB: Supporting the Immune System's Natural Brakes

Resveratrol also shows promise in treating the most common autoimmune diseases appearing post COVID and post Spike Protein exposure.

Molecular Mimicry and FcγRIIB: Is the Spike Protein Teaching the Immune System to Disable Its Own Brakes?

A recent review of autoimmune conditions occurring post-COVID show connective tissue disorders at the top of the list – and FcγRIIB dysfunction may be a culprit.

Friday Hope: Berberine, Resveratrol and Curcumin — A Compelling Foam-Cell Trifecta?

Attacking the foam-cell problem from complementary directions.