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Stimulating Brains

Andreas Horn interviews experts in the field of deep brain stimulation, noninvasive neuromodulation, functional brain imaging and neuroanatomy. Join us on our quest to interact with the human brain and thank you for your interest in science! Andreas Horn, M.D., Ph.D., directs the institute for network stimulation and is a professor for computational neurology at University Cologne.

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#82: Doris Wang – Adaptive DBS, the Rhythm of Walking, and Restoring Human Movement

Doris D. Wang is an associate professor of neurological surgery at the University of California, San Francisco, a functional neurosurgeon specializing in movement disorders, and a systems neuroscientist studying how human brain circuits generate and restore movement. In this episode of Stimulating Brains , we focus on her new study in Nature Medicine . In five people with Parkinson’s disease, her…

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#81: Theodore Schwartz - Gray Matters: brain surgery from the inside, the history and the future of neurosurgery

Theodore H. Schwartz is a neurosurgeon, author, and the David and Ursel Barnes Endowed Professor of Minimally Invasive Neurosurgery at Weill Cornell Medical Center and New York-Presbyterian Hospital. In this episode of Stimulating Brains, we talk about his book Gray Matters: A Biography of Brain Surgery, a vivid account of what brain surgery really is – personally, technically, historically,…

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#80: Michael Okun - The Parkinson's Plan, prevention, care, and the future of Parkinson's disease

In this episode of Stimulating Brains, I am delighted to welcome back Michael Okun, neurologist, movement-disorders specialist, Adelaide Lackner Distinguished Professor of Neurology at the University of Florida, Director of the Norman Fixel Institute for Neurological Diseases, and National Medical Advisor of the Parkinson's Foundation. Mike was previously on the podcast in episode 25 together with…

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#79 Karl Friston: The Origins of SPM and the Making of Modern Human Brain Mapping

Karl Friston is one of the most influential neuroscientists of our time and a central figure in the history of human brain mapping. Many listeners will know him for the free energy principle, active inference, dynamic causal modeling, voxel-based morphometry, and many other theoretical contributions. In this episode, we take a different route and go back to the early history of Statistical…

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#78: Keith Mullett — Medtronic, pain, and the prehistory of modern DBS

In this episode of Stimulating Brains, I speak with Keith R. Mullett, who can uniquely tell a part of the DBS history that is often skipped. We often begin the story of modern DBS in Grenoble around 1987, when Alim-Louis Benabid and colleagues showed that high-frequency VIM stimulation could suppress tremor. Keith reminds us that Medtronic's first DBS system had already been implanted in 1969, not…

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#77: Mary Elizabeth Sutherland — Nature, editorial judgment, and the future of scientific publishing

In this episode of Stimulating Brains, I’m honored to speak with Mary Elizabeth Sutherland, a Deputy Editor at Nature whose areas of responsibility include cognitive neuroscience and a broad range of the behavioural and social sciences. If you work with clinical or human neuroscientific data in the field of brain stimulation and choose to submit to Nature, chances are high that Mary Elizabeth will…

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#76: György Buzsáki — Action, the ultimate source of knowledge

In this episode of Stimulating Brains , we are honored to sit down with György Buzsáki, Professor of Neuroscience at New York University and one of the most influential thinkers in modern neuroscience. Dr. Buzsaki trained as a physician in Hungary, completed his PhD in neuroscience at the Hungarian Academy of Sciences, and went on to postdoctoral training in North America before building a…

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#75: Frans Gielen – From Idea to Evidence: The Making of Modern DBS

In today’s episode of Stimulating Brains, we have the pleasure of speaking with Frans Gielen — a physicist and biomedical engineer who played a foundational role in shaping modern deep brain stimulation. Over more than three decades at Medtronic, Frans worked at the intersection of engineering, neurology, and surgery during the formative years of DBS, when stereotactic imaging protocols, targeting…

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#74: Ludvic Zrinzo – DBS vs. Lesioning – and how to know you’re right

In this episode of Stimulating Brains , we sit down with Dr. Ludwig Zrinzo, Professor of Functional Neurosurgery at University College London and Head of the Functional Neurosurgery Unit at Queen Square. Drawing on decades of experience at the forefront of deep brain stimulation, Dr. Zrinzo reflects on the evolution of DBS from awake procedures to image-guided surgery under general anesthesia,…

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#73: Eyal Zadicario – Beyond the Scalpel: Towards an Acoustic Neurosurgical Suite with Insightec

In this episode of Stimulating Brains , we sit down with Dr. Eyal Zadicario, Chief Operating Officer at Insightec, to explore the remarkable evolution of focused ultrasound – from its experimental origins to its transformative role in functional neurosurgery today. Dr. Zadicario shares insights from over two decades at the forefront of innovation, reflecting on the challenges of translating…

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