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Eat Shit and Prosper

The greatest unexplored frontier in human health and disease: the gut microbiome

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On the Origins of Peanut Allergy

Before 1980, peanut allergy was so rare that the idea of someone dying from it was preposterous. So what changed?

A Bone to Pick

How I became a biblical literalist

Oops! We have been spraying diabetes drugs on the crops.

This is good news. But not in the way you might think.

Lab-Grown Meat is a Pipe Dream. We Need Lab-Grown Cheese.

Luck got us cheese, chocolate, and wine. What could we create if we really put our minds to it?

Now Recruiting: The Cassiopeia Program

A hypothesis post that is also a study signup form that is also behind a CDA.

The Problem With Beta-Carbolines, Part III

Some armchair-testable predictions about psychotic disorders

The Problem with Beta-Carbolines, Part II

Doomed to Repeat: Fully bogus findings from one of America's most prestigious universities.

The Problem with Beta-Carbolines, Part I

Q: What do ayahuasca, the human vagina, and an alcoholic have in common?

The Statue in the Cave

Large Language Models can't even handle poop science. How are they supposed to help us create a super-intelligent AI?

Symbiosis as a Business Model

The economics of cures