Ep.43 - Jürgen Claesen : Atomic Measurements To Big Data

Jürgen Claesen is an Assistant Professor of Epidemiology and Data Science at Amsterdam UMC, affiliated with VU Amsterdam, and a guest lecturer at the Data Science Institute, Hasselt University. His research focuses on the development of statistical and computational methods for high-throughput biological experiments.

• Research Expertise: His work is primarily focused on high-dimensional omics, specifically in the fields of sequencing and mass spectrometry.

• Specialized Methodologies: He has extensive experience in structural bioinformatics, computational proteomics, and next-generation sequencing.

• Key Research Themes:

  • Immune Age: He contributed statistical methodology to recent research developing metrics that predict outcomes in clinical patients using T-cell-based immune age data.

  • Mass Spectrometry: A significant portion of his research involves Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS) and developing computational tools for structural biology.

  • Radiation and Microbiology: His research has explored the effects of radiation on microbial communities, including intestinal dysbiosis in irradiation models and soil microbial changes from long-term radionuclide contamination.