Part2: Neuroinflammation, New “Pandemic Seizures” and Good Clinical Work exemplified in this article from 2025

See also my previous article on Intracellular Hypercalcinosis.

1. Trousseau’s sign is a clinical indicator of low blood calcium (hypocalcemia) or high nerve and muscle sensitivity (neuromuscular excitability). It causes the hand and wrist to spasm into a flexed position when a blood pressure cuff is inflated above the systolic pressure for two to three minutes.

2. Chvostek Sign: How to test: Tap gently on the facial nerve, located right in front of the ear just below the zygomatic arch (over the masseter muscle). Positive result: A brief twitch or spasm of the facial muscles (such as the corner of the mouth or the side of the nose) on the side being tapped. Clinical note: It is less reliable because roughly 10–25% of healthy people can test positive, and some patients with true hypocalcemia may not show it.

3. Note the very impressive laboratory results reported in this article: the two tests that I highlighted are tests that clinicians should be using in the evaluation of these more severe cases, in addition to the usual serum calcium and 25ohD.

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1. Chronic pain and pain amplification,

2. Mood, depression, anxiety,

3. Barrier defense against infection, allergy, autoimmunity,

4. Inflammation and immunomodulation,

5. Antimicrobial Antiviral Defense against Clinically Important Viral Infections

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