Having a “3-repeat” genotype for the MAO-A gene means possessing the low-activity variant of the Monoamine Oxidase A enzyme (commonly referred to as MAOA-L) (Sun et al., 2020). When a report notes “3 homozygosities” (or homozygous 3R), it means that across the relevant genetic markers tested, you carry two copies of this lower-expressing allele (e.g., if you are female, as the MAO-A gene resides on the X chromosome) (Deckert et al., 1999; Kolla & Bortolato, 2020).
Understanding how this genotype influences neurotransmitters provides clear direction on how to manage the associated anxiety using both natural and pharmaceutical approaches.
Comments
Nothing yet. Say the first thing.
Sign in to join the conversation.