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Brain Inflammation Collab · Aug 20, 2026

Why Are Autoimmune Diseases on the Rise?

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Brain Inflammation Collab · Brain Inflammation Collab

Between the years 1950 and 2000, the following autoimmune conditions increased by 300%:
- Crohn's disease
- Multiple sclerosis
- Type 1 diabetes mellitus

Is this a problem endemic to the Western world?
In 🇵🇰 Pakistan, the incidence of Type 1 Diabetes is 1 in 100,000 people.
In the 🇬🇧 U.K., the incidence of Type 1 Diabetes is > 1 in 10,000 people (>10x).

However, the rate of T1D in Pakistani children who moved to the UK increased roughly 10x to reflect the rate of T1D observed among U.K. residents.

This suggests 🧬 can't take all the blame. In reality, it's a combination of 🧬 + environmental factors that cause chronic inflammation, such as:
- chronic infections (EBV, HSV, etc)
- lack of physical activity
- ultra-processed foods
- environmental toxins
- forever chemicals
- sleep problems
- chronic stress
- polluted air
- etc.

Could chronic inflammation be contributing to increased autoimmunity in Western nations?

Leave a comment below and let us know what you think.

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Read the original on braininflcollab.substack.com

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