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The Last Great Mystery

Transformation and transcendence through biotechnology

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Latest episodes

Hype and hope at SynBioBeta 2026

the synbio conference at the end of history

Talking to Cetaceans

what would you ask a whale?

Biotech's fabless future

Building the TSMC of industrial biotech

Making Biomanufacturing Great Again

I went on the Human3 Podcast with Brom and Sam

Where to locate your startup

Location matters, but how much?

Billion Dollar Bioproducts

Industrial biotech's greatest hits

Introducing Biosphere

unleashing industrial biology

10x better fermentation infrastructure at massive scale

The only way to unleash our biomanufactured future

Deeptech Seed Fundraising

or: how I learned to stop worrying and love the raise

How to spend $2b on Biomanufacturing

Biden Bucks for Bio

The best of times & the worst of times in synbio

Sell your bioproduct or die trying

The Future of Biology is Quantum

A proposal for a new scientific research organization

A global grain crisis 🌾

a perfect storm in the wheat market could portend something much bigger

Engineered probiotics FTW

a new class of GMO products that actually work

labDAO: a deeptech R&D engine for startup cities

decentralized science to empower new communities

Biotech + Climate

brb gonna make some super-trees

Omicron origins

a work of fiction... right?

Ferment all the things!

a short intro to all things biomanufacturing

Learning as we build labDAO

Want to learn about DAOs? Start one!

Building a labDAO for web3 biotech

How can we leverage global lab networks to accelerate R&D?