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fahb - Design and Analysis of Pilot Trials Assessing Recruitment Feasibility
Find optimal decisions rules for guiding progression decisions following a pilot trial, assuming a hierarchical recruitment model. Estimate the time until the main trial recruits to target, given the recruitment data observed in the pilot.
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4.90 score 4 scripts 192 downloads
tout - Optimal Sample Size and Progression Criteria for Three-Outcome Trials
Find the optimal decision rules (AKA progression criteria) and sample size for clinical trials with three (stop/pause/go) outcomes. Both binary and continuous endpoints can be accommodated, as can cases where an adjustment is planned following a pause outcome. For more details see Wilson et al. (2024) <doi:10.1186/s12874-024-02351-x>.
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4.54 score 5 scripts 131 downloads