ADGRF4

ADGRF4
Identifiers
Aliases	ADGRF4, PGR18, GPR115, adhesion G protein-coupled receptor F4
External IDs	OMIM: 614268; MGI: 1925499; GeneCards: ADGRF4
Gene location (Human)
Chr.	Chromosome 6 (human)
End	47,722,021 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	43,003,175 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; skin of leg; ; skin of arm; ; gingival epithelium; ; human penis; ; right uterine tube; ; amniotic fluid; ; skin of thigh; ; vagina; ; oral cavity;
	Top expressed in
	decidua; ; skin of external ear; ; gastrula; ; lip; ; molar; ; skin of abdomen; ; skin of back; ; embryo; ; epidermis; ; hair follicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	221393
	78249
	ENSG00000153294
	ENSMUSG00000023918
	Q8IZF3
	Q9D2L6
	NM_153838; NM_001347855
	NM_001289499; NM_001289500; NM_001289501; NM_030067
	NP_001334784; NP_722580
	NP_001276428; NP_001276429; NP_001276430; NP_084343
	Wikidata
View/Edit Human	View/Edit Mouse

Adhesion G protein-coupled receptor F4 is a protein that in humans is encoded by the ADGRF4 gene (previously GPR115).^[5]^[6] The ADGRF4 protein is an orphan receptor which is part of the adhesion family of G protein-coupled receptors.^[7]

References

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

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