Reading · AlleyCorp’s Newsletter

The last several years have been among the most exciting in our firm’s history.

Three years ago, we raised outside capital for the first time with our $250 million fund. Today, we’re proud to build on that with the close of AlleyCorp Fund II at $335 million.

For those who have spent the last three decades building and investing in startups, it’s hard to overstate just how exciting it is to be working in tech right now. The pace at which new companies are being built is extraordinary. Founders are moving faster than I’ve ever seen, and they’re using less capital and significantly smaller teams to do it.

The products and platforms we’re seeing in initial pitch meetings would have been unimaginable for a pre-seed or even seed-stage company just a few years ago. It’s why we believe now is the right time to double our focus and deepen our commitment to backing founders at the earliest stages of company creation.

In healthcare, companies like Thyme Care and Pearl Health have demonstrated enormous opportunity in value-based care, while our conviction in AI’s medical impact has only grown through investments in Pathway Labs, Rhino FCP, and others.

Across enterprise and software, companies like Rogo are building category-defining applications, while ShopMy and Agentio are bringing businesses and consumers more meaningful ways to interact.

And in deep tech — an increasingly important focus for us — we’ve expanded our investments across energy, space, industrial systems, and infrastructure by backing ambitious companies like Valar Atomics, Portal Space Systems, and Radical AI, who are tackling some of the biggest industrial challenges of our time.

With eight unicorns now in our portfolio, it’s a privilege to be working with so many inspiring founders.

There’s really nothing more fun and rewarding than getting to build alongside so many incredible people.

AlleyCorp co-led Vanna Health’s $17M funding round alongside a national healthcare insurance company, with participation from Health Velocity Capital.

Founded to close the gaps in treating serious mental illness, including schizophrenia and bipolar disorder, Vanna Health deploys a tech-enabled model to support lasting recovery and wellbeing. The new funding will enable Vanna to accelerate its expansion into new markets and grow its clinical and operational teams.

Read more in Behavioral Health Business.

AlleyCorp led Queue’s $12.6M Seed Round with additional investors including Riot Ventures, House Capital, Ubiquity Ventures, Grep Ventures, and Banter Capital.

Queue has built the world’s first, fully autonomous robotic pharmacy, designed to transform how prescriptions are dispensed, verified, and delivered.

Read more from TechCrunch.

This month, AlleyCorp kicked off the first of our new event series, Journal Club, where we invite fellow doctorpreneurs and physician innovators to discuss newly released articles, highlighting the topics that are shaping medicine and healthcare.

Our first Journal Club focused on the recent Nature paper, analyzing general-purpose LLMs and how they may be outperforming more specialized medical AI tools.

Earlier this summer, we officially opened our new company headquarters at 368 Broome St.

We look forward to hosting many tech and founder gatherings on our new rooftop and indoor lounge. If you’re interested in hosting your next event with us, please reach out to events@368broome.com for more info.

On the ground floor of the building, we also opened Oriana, a new wood-fired restaurant from Chef Andy Quinn and Sommelier Cedric Nicaise, alongside Frenchette, the bakery from James Beard award-winning restaurateurs Lee Hanson and Riad Nasr.

Keep an eye out for more updates on our three marquee events, bringing together thousands of founders, investors, industry leaders, and execs across tech, healthcare, and more.

Digital Health New York (DHNY): Sept. 17, 2026 - Registration is now open for DHNY’s fifth annual summit with mainstage talks featuring leadership from Google, Mount Sinai, Weill Cornell Medicine, Doctronic, CBS News, and more.
DOC: Oct. 21-23, 2026 - Our longevity-focused conference returns to Sonoma, CA for its third-annual gathering, cutting through the noise with evidence-based talks from DOC’s community of scientists.
Deep Tech New York (DTNY): Apr. 15, 2027 - Just announced, DTNY will return to Newlab in Brooklyn next year for a full-day of programming centered on the technologies that will define the next 50 years of science and innovation.

Brannon Jones spoke on the future of quantum computing and photonics at J.P. Morgan’s Tech Week event in NYC.
- In June, Brannon also joined the Kauffman Fellows, as a member of their newest class of VC leaders.
Susannah Shipton highlighted her unique career path from platform to investment partner at the annual VC Platform Summit. Lauren Young also spoke at the summit, outlining the best ways for VCs to prioritize and systematize platform functions.
Omar Njie was a guest lecturer at Columbia Technology Ventures, leading a discussion on early-stage startup formation and healthcare commercialization strategies.
Abe Murray was busy across the university speaker circuit, visiting Carnegie Mellon, MIT, and Columbia for a range of talks on new nuclear frontiers and future innovations across climate, energy, and robotics.
Marshall Porter will take the stage at Foundry’s CIO Summit to highlight key trends across vertical AI applications.
Episodes 2 and 3 of our new Deep Tech podcast, The Long Frontier, aired last month. The first featured Dr. Hon Weng Chong of Cortical Labs in a mind-blowing conversation that explored the future of biological computing — how living neurons can create adaptive neural computing systems. The second unpacked the world of nuclear fusion with Dr. Ahmed Diallo of Princeton Plasma Physics Laboratory. Listen to both here!

AlleyCorp is excited to welcome Bree Piperwilliams to the team as our new Events Manager, helping to oversee a wide range of events — from annual summits and NYC community gatherings to portfolio programming and experiences at The AlleyCorp Building.

Prior to AlleyCorp, Bree was Head of Events at Manifest, where she scaled the company’s events program. She also previously led strategic operations at Munich Re Ventures which included overseeing flagship conferences, founder summits, executive dinners, and curated experiences for industry leaders.

Fast Company profiled Radical AI, taking a first look inside the company's autonomous lab, where AI is dramatically accelerating the discovery of next-generation materials.
Thyme Care was named to CNBC’s Disruptor 50 list, highlighting the company’s unique ability to deliver value-based care in the oncology field.
- Co-founder and CEO, Robin Shah, later joined CNBC Fast Money to discuss the impactful ways they are working with more than 120k cancer patients.
Valar Atomics successfully achieved criticality as part of the U.S. Department of Energy’s Reactor Pilot Program. In July, Valar also became the first US nuclear startup to produce power from an advanced reactor.
Financial Times wrote a feature on ShopMy — and its star-studded appearance at the Met Gala — showcasing how creators are earning hundreds of thousands of dollars each month on the platform.
Rogo was recognized on Forbes’ 2026 AI 50 list, spotlighting the leaders driving the future of AI.
For Wellness co-founder Greg Banbury was named a finalist for EY’s Entrepreneur of the Year award, earning the recognition for his work as a leader in health and wellness.
Clarium founder Steve Liou joined Becker’s Healthcare Podcast to discuss how better data and automation in hospitals’ supply chains can unlock billions in savings.
Appetronix acquired food robotics startup Cibotica, integrating its automated bowl and salad assembly system into Appetronix’s multi-cuisine restaurant platform.
Rhino FCP was named to CB Insights’ AI 100 list, selected for their leadership in the Infrastructure and Compute category.
Agentio founder Arthur Leopold joined the Scalable Summit for a conversation with Visa’s CMO, Frank Cooper III, and Adobe’s Chief Content & Creative Officer, Stacy Martinet, on how far creator advertising has come.

AlleyCorp's New $335M Fund

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