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Two Scientists Walk Into a Bar

From research on cancer vaccines to why we feel pain, scientists are tackling some of the biggest challenges in human biology. Want to find out what they’re working on? Pull up a stool for "Two Scientists Walk Into a Bar." Subscribe below to catch each episode as it goes live.

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S7E05: AI in Oncology

How can artificial intelligence help our scientists find the hidden patterns in cancer's complex biology? In this episode, host Danielle Mandikian is joined by Anwesha Dey, Distinguished Scientist and Executive Director of AI - Oncology and Cancer Biology, to talk about the new reality of the oncology lab. They explore how teaming up with artificial intelligence allows researchers to challenge…

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S7E04: Lab of the Future

Are we on the cusp of a new era in scientific research? This episode delves into the transformative potential of the "lab of the future." Host Danielle Mandikian and guests Margaret Porter Scott, VP, Biochemical Cellular Pharmacology, and Andy Lash, Head of Engineering, Lab Automation, discuss how AI and automation are set to tackle major bottlenecks in science, from fragmented systems to the…

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S7E03: The ABCs of IBD

Inflammatory bowel disease (IBD) is a debilitating, lifelong condition that changes how people plan their entire lives. In this episode, KT Park, Global Head of Gastroenterology and Hepatology, and Seppi Lin, Head of OMNI Early Clinical Development, explore the complex biology behind IBD. They discuss the role of genetics, the gut microbiome, and an individual’s environment, as well as the…

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S7E02: Breakthroughs in MS

Breakthroughs in the last decade have transformed how we understand and treat multiple sclerosis (MS), but what will it take to stop the disease in its tracks? Pull up a stool with co-host Maria Wilson and our guest Sherman Jia, Group Medical Director, gRED Translational Medicine, for a discussion on the breakthrough research into B cells that has made a "night and day" difference for people…

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S7E01: The Wild World of Eyeballs

We’re kicking off season seven with an in-depth look at the wild world of ophthalmology, where scientists are pushing the boundaries of what’s possible for vision treatments. In this episode, co-host Danielle Mandikian is joined by guests Deepak Lamba, Director and Distinguished Scientist, Ophthalmology, and Susie Crowell, Senior Director, Project Team Leader, to explore the latest in the field of…

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Season Seven Teaser

Your favorite science podcast is back! To kick off season seven of Two Scientists Walk Into a Bar, hosts Maria Wilson and Danielle Mandikian sit down to celebrate a decade of the podcast and look back at our previous season on unmet medical needs. But what’s next? Get ready for a season that’s going bigger than ever before. To mark the 50th anniversary of Genentech, Maria and Danielle will draw a…

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S6E07: Foundation Models and Agents

In our season six finale, we dive deeper into how artificial intelligence (AI) is shaping the future of drug discovery and scientific research. With remarkable scale and speed, AI models parse through complex datasets and confirm or generate hypotheses, which can help scientists accelerate R&D. In this episode, co-host Danielle Mandikian welcomes Aviv Regev, Head of gRED, and Jure Leskovec,…

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S6E06: Decoding Lung Disease

From our first breath, the air we breathe and our genes shape how our lungs function. It’s a complex interplay we began exploring in our season four episode “Take A Deep Breath: Treating Asthma.” Today, we’re branching out to discuss lung biology and the diseases that make it difficult to breathe. In this episode, co-host Maria Wilson speaks with Dorothy Cheung, Executive Group Medical Director,…

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S6E05: Cells at Work

Cell therapy holds immense potential to transform the way we treat conditions in oncology, ophthalmology, autoimmune disorders, and a wide range of other therapeutic areas. But how do these engineered cells work, and how do scientists ensure they are safe and function as intended? In this episode, co-host Danielle Mandikian sits down with Todd McDevitt, Head of Cell Therapy, to discuss how cell…

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S6E04: The Power of Digital Twins

Digital twins are virtual models of real-world systems that have been gaining momentum as a powerful tool in drug discovery and development. We touched on this concept last season when we covered computational advancements in drug discovery. Now, we’re taking a deeper dive into the power of digital twins. By leveraging genomics, physical health data, lab results, and other clinical datasets,…

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