Higher BMI Significantly Reduces Effectiveness Of JAK Inhibitors In Rheumatoid Arthritis

New Delhi, August 20, 2026 | Obesity directly reduces how well JAK inhibitors work in rheumatoid arthritis, according to a new individual patient data meta-analysis. Researchers found that as BMI increases, treatment response to drugs like tofacitinib, baricitinib and upadacitinib drops steadily, with class 3 obesity patients showing the largest...