1,3-Dipolar Cycloadditions

Cycloadditions provide a controlled method for the construction of ring systems. 1,3-Dipolar cycloadditions form five-membered heterocycles. Electronically, these reactions involve 4+2 π electrons & are analogous to Diels-Alder reactions. They are concerted reactions (mostly) & the geometry of the dipole & the dipolarophile are preserved in the stereochemistry of the product. Unlike Diels-Alder…