Amyloid and tau: what we know about how Alzheimer’s disease develops

Every brain affected by Alzheimer's disease carries two telltale signs: sticky clumps of a protein fragment called amyloid-beta, and tangled threads of another protein called tau. Scientists have studied both for decades. Yet a comprehensive new scientific review, published in the journal Cell Death & Disease, makes one thing clear: we still don't fully understand how these two proteins cause the…