# oncology (blogs) — RSS Amplifier Recent posts from the 20 feeds in the RSS Amplifier directory that cover oncology. Page: Feed: --- ## [Before its recent Phase 3 LSD win, Definium modeled up to $70,000 a year for a therapy that could fill a clinical shift](https://www.drugdiscoverytrends.com/before-its-recent-phase-3-lsd-win-definium-modeled-up-to-70000-a-year-for-a-therapy-that-could-fill-a-clinical-shift/) _2026-08-21 · Brian Buntz · Drug Discovery and Development_ New York City–based Definium recently announced positive data from its Phase 3 Voyage trial of DT120, an orally disintegrating 100 µg dose of LSD in adults with generalized anxiety disorder (GAD). The company announced positive Phase 3 results for the same compound for major depressive disorder (MDD) in June. Now the company needs to convince… The post Before its recent Phase 3 LSD win, Definium… ## [Positive psychotherapy may be similarly effective to traditional cognitive behavioural therapy for panic disorder](https://www.2minutemedicine.com/positive-psychotherapy-may-be-similarly-effective-to-traditional-cognitive-behavioural-therapy-for-panic-disorder/) _2026-08-21 · Paary Balakumar · Chronic Disease | 2 Minute Medicine_ 1. Positive Psychotherapy (PPT) produced anxiety and well-being outcomes statistically comparable to standard CBT, suggesting it may be a viable alternative for patients who do not respond to or prefer not to pursue traditional exposure-based treatment. 2. Both interventions demonstrated durable, clinically meaningful improvement sustained at three-month follow-up in an online group format… ## [EV-Pembro Beats Chemo in Muscle- Invasive Bladder Cancer](https://www.oncologynewscentral.com/bladder-cancer/perioperative-combination-beats-chemo-in-muscle-invasive-bladder-cancer) _2026-08-21 · ONC_ Perioperative enfortumab vedotin plus pembrolizumab significantly improved survival compared with cisplatin-based chemotherapy in muscle-invasive bladder cancer. ## [Liver Health in Metabolic Protocols: A Comprehensive Guide to Recovery, Protection, and Detoxification](https://oncologytruth.substack.com/p/liver-health-in-metabolic-protocols-823) _2026-08-21 · Repurposed Oncology · Repurposed Oncology_ Dear Readers, I receive numerous questions regarding liver safety when using advanced metabolic protocols based on Ivermectin and Benzimidazoles(Mebendazole/Fenbendazole). ## [Metabolic stability: The defining challenge for multifunctional peptides](https://www.drugdiscoverytrends.com/metabolic-stability-the-defining-challenge-for-multifunctional-peptides/) _2026-08-20 · Dr. Hanlin Tao, Haijuan Liu · Drug Discovery and Development_ The demand for peptide therapeutics has grown rapidly in recent years, as the success of GLP-1 drugs has catapulted them to the forefront of developers’ and sponsors’ minds. Although peptides still represent a relatively small share of FDA-approved therapeutics, they offer distinct advantages in treating diseases where small-molecule drugs or therapeutic antibodies fall short. The… The post… ## [MUST KNOW METRICS regarding the reliable synergy protocol of EGCG zinc and DCA inside a 5 day on and 2 day off schedule and a professional analysis of tumor apoptosis](https://oncologytruth.substack.com/p/must-know-metrics-regarding-the-reliable) _2026-08-20 · Repurposed Oncology · Repurposed Oncology_ The Metabolic Synergy- Why DCA, EGCG, and Zinc Form the Ultimate Cellular Trap ## [Is It Time for a New Type of Cancer Physician?](https://www.oncologynewscentral.com/video/oncology/is-it-time-for-a-new-type-of-cancer-physician) _2026-08-20 · ONC_ The dramatic increase in cancer survivorship is introducing questions about the ability of physicians to meet patient needs. Is it time to create a specialty for “survivorship physicians?” ## [Sonali M. Smith, MD](https://www.oncologynewscentral.com/contributor/sonali-m-smith) _2026-08-20 · ONC_ Sonali M. Smith, MD, is the Elwood V. Jensen Professorship of Medicine and the chief, section of hematology/oncology at UChicago Medicine. ## [Em Shone, BSN, RN, OCN](https://www.oncologynewscentral.com/contributor/em-shone) _2026-08-20 · ONC_ Em Shone, BSN, RN, OCN, is an oncology nurse located in Houston, Texas. ## [Shervin Tabrizi, MD](https://www.oncologynewscentral.com/contributor/shervin-tabrizi) _2026-08-20 · ONC_ Shervin Tabrizi, MD, is an assistant professor of radiation oncology at the Perelman School of Medicine in Philadelphia, Pennsylvania. ## [A Friend Gave You $30 (Sponsored)](https://crawlproof.com/a/Kp9b20g5C2Jw) _2026-08-20 · **Sponsored**_ Sign up, deposit $5 within 30 days, and start investing with expert guidance. ## [Miriam Adina Knoll, MD](https://www.oncologynewscentral.com/contributor/miriam-knoll) _2026-08-20 · ONC_ Miriam A. Knoll, MD, is a clinical assistant professor of medicine at the Donald and Barbara Zucker School of Medicine at Hofstra University/Northwell Health in Glen Oaks, New York. ## [Combo Shows Survival Benefits in Advanced Breast Cancer](https://www.oncologynewscentral.com/breast-cancer/giredestrant-plus-everolimus-extends-postprogression-benefit-in-advanced-breast-cancer) _2026-08-20 · ONC_ Giredestrant plus everolimus improved progression-free survival after subsequent therapy and chemotherapy-free survival in ER-positive, HER2-negative advanced breast cancer. ## [Spaghetti with Fresh Tomato, Basil, Brown Butter and Parmigiano](https://nutmegphantasy.substack.com/p/spaghetti-with-fresh-tomato-basil) _2026-08-20 · Hans Casteels · The Oncology Underground_ Hans Casteels ## [As 59% fewer pharma companies cut staff in Q2 in 2026, job postings rise 15%](https://www.drugdiscoverytrends.com/as-59-fewer-pharma-companies-cut-staff-in-q2-in-2026-job-postings-rise-15/) _2026-08-20 · Brian Buntz · Drug Discovery and Development_ 2022 was a big year for layoffs in biopharma. So were the next three. Novartis, for instance, outlined plans to cut up to 8,000 jobs in 2022, after pharmaceutical industry job cuts jumped 280% in 2021. Biogen followed in 2023 with a “Fit for Growth” program that put roughly 1,000 roles on the block. Bristol… The post As 59% fewer pharma companies cut staff in Q2 in 2026, job postings rise 15%… ## [Brain-predicted age difference may reliably predict dementia progression](https://www.2minutemedicine.com/brain-predicted-age-difference-may-reliably-predict-dementia-progression/) _2026-08-19 · Paary Balakumar · Chronic Disease | 2 Minute Medicine_ 1. Brain-predicted age difference (brain-PAD) is a robust, reproducible predictor of dementia progression across two independent estimation methods, and it is most clinically useful in subjective cognitive decline, where it can help identify low-risk patients and reassure the “worried well,” rather than in mild cognitive impairment, where visual rating scales already capture most prognostically… ## [The official rebellion of a British professor in London and how ivermectin and mebendazole strip away the immune blanket and a deep analysis of Turbo Cancers](https://oncologytruth.substack.com/p/the-official-rebellion-of-a-british) _2026-08-19 · Repurposed Oncology · Repurposed Oncology_ The Oncology Rebellion: Why Old Molecules Are Breaking the Medical Silence ## [News Scan](https://www.oncologynewscentral.com/news-scan) _2026-08-19 · ONC_ A quick review of oncology headlines that matter most. ## [Who decides in the EU?](https://pharmaceuticaldaily.com/who-decides-in-the-eu/) _2026-08-19 · Dino Mustafić · pharmaceutical daily_ Out of five Croatians in Brussels, roughly one in five Croatians decided who would speak for the other four in… ## [The Day the Future Finally Stopped Moving](https://nutmegphantasy.substack.com/p/the-day-the-future-finally-stopped) _2026-08-19 · Hans Casteels · The Oncology Underground_ By Hans Casteels. Ruminating on the forbidden relief that can arrive when uncertainty finally gives way to truth, and why laying down the fight is not the same as surrender. ## [How Sheba Medical Center became OpenAI’s first international hospital partner](https://www.drugdiscoverytrends.com/how-sheba-medical-center-became-openais-first-international-hospital-partner/) _2026-08-18 · Brian Buntz · Drug Discovery and Development_ OpenAI’s first international hospital partnership is taking shape at a giant medical center where English is not the default language and where the electronic health record does not come from Epic, the dominant U.S. EHR vendor. That institution is Sheba Medical Center, the Israel-based medical center with its own 50-plus-person AI Center within ARC, its… The post How Sheba Medical Center became… ## [Pirate.io on Google Play (Sponsored)](https://crawlproof.com/a/CBQNkL1FjxJc) _2026-08-18 · **Sponsored**_ Open the Pirate.io listing on Google Play to view the app’s details. ## [Challenging Clinical Case: A Pickleballer With CLL](https://www.oncologynewscentral.com/cll/challenging-clinical-case-a-71-year-old-retired-pickleballer-with-cll) _2026-08-18 · ONC_ A 71-year-old retired engineer who regularly plays pickleball is preparing to undergo treatment for his CLL. How much do you know about treatment options and pivotal trials that inform care? ## [FDA issues final PDUFA meeting guidance, expands use of written responses](https://www.drugdiscoverytrends.com/fda-issues-final-pdufa-meeting-guidance-expands-use-of-written-responses/) _2026-08-18 · Julia Rock-Torcivia · Drug Discovery and Development_ The FDA has finalized new guidelines for meetings between the FDA and sponsors or applicants relating to the development and review of drugs or biological products under the Prescription Drug User Fee Act (PDUFA). The FDA first published the draft guidance on Sept. 22, 2023, when it collected public comment on the guidelines. The final guidelines contain several changes from the draft, including… ## [How to integrate ivermectin and fenbendazole alongside safe fasting into a modern cancer protocol and a precise analysis of chronobiological windows (VIDEO)](https://oncologytruth.substack.com/p/how-to-integrate-ivermectin-and-fenbendazole) _2026-08-18 · Repurposed Oncology · Repurposed Oncology_ Introduction: A New Perspective on Stress Resistance and Cellular Hunger Logistics ## [Oncology News Central](https://www.oncologynewscentral.com/) _2026-08-18 · ONC_ Oncology News Central ## [Letters From Oliver: Isabel’s Continuing Education](https://nutmegphantasy.substack.com/p/letters-from-oliver-isabels-continuing) _2026-08-18 · Hans Casteels · The Oncology Underground_ By Hans Casteels, who swore up and down that she would not be spoiled. He was wrong as usual. ## [New Book Provides “Window to the Entirety of Oncology”](https://www.oncologynewscentral.com/cll/new-book-provides-window-to-the-entirety-of-oncology-through-the-history-of-cll) _2026-08-18 · ONC_ The past and future of CLL care are presented as “a window to the entirety of oncology” in \*Ghosts in the Blood\*, set for release this September. ## [Community Oncology Alliance](https://www.oncologynewscentral.com/partners/community-oncology-alliance) _2026-08-18 · ONC_ Serving as the voice of community oncology in Washington, DC, and across the country, the Community Oncology Alliance (COA) aims to improve patient care, offer professional growth for cancer care providers, and support practice operations. Individuals from every level of the cancer care delivery team, including oncologists, hematologists, pharmacists, oncology nurses and nurse practitioners,… ## [Meet Community Oncology’s “Energizer Bunny”](https://www.oncologynewscentral.com/oncology/meet-community-oncologys-energizer-bunny) _2026-08-18 · ONC_ Harsha Vyas, MD, founded rural Georgia’s only physician-owned oncology practice 14 years ago. Here’s how he has kept cancer care flourishing where it didn’t before. ## [Gilead and Nucleai probe why target-positive tumors can still resist ADCs](https://www.drugdiscoverytrends.com/gilead-and-nucleai-probe-why-target-positive-tumors-can-still-resist-adcs/) _2026-08-18 · Brian Buntz · Drug Discovery and Development_ Antibody-drug conjugates (ADCs) have emerged as one of the busiest and most crowded niches within oncology, given their potential to use an antibody to ferry a potent cytotoxic payload toward tumor cells. The class now spans about 15 FDA-approved products, and the segment is growing steadily. Evaluate Pharma projects the ADC category will reach $57… The post Gilead and Nucleai probe why… ## [A neurostimulation intervention may improve pain in patients with chronic low back pain](https://www.2minutemedicine.com/a-neurostimulation-intervention-may-improve-pain-in-patients-with-chronic-low-back-pain/) _2026-08-17 · Paary Balakumar · Chronic Disease | 2 Minute Medicine_ 1. Restorative neurostimulation produces durable, clinically meaningful improvements in pain, disability, and quality of life at 5 years in real-world chronic mechanical low back pain patients. Evidence Rating Level: 3 (Average) This 5-year follow-up study evaluated restorative neurostimulation (ReActiv8) for chronic mechanical low back pain (CLBP) attributed to multifidus dysfunction. Restorative… ## [Ship everywhere from one CLI (Sponsored)](https://crawlproof.com/a/9ov4vABFYHMb) _2026-08-17 · **Sponsored**_ One codebase, hosted runners, encrypted credentials, and automated submissions across stores ## [Schrödinger-BMS collaboration centers on Bunsen for trillion-scale computational drug discovery](https://www.drugdiscoverytrends.com/schrodinger-bms-collaboration-centers-on-bunsen-for-trillion-scale-computational-drug-discovery/) _2026-08-17 · Brian Buntz · Drug Discovery and Development_ The 1990-founded scientific software firm Schrödinger recently announced a strategic collaboration and software agreement with Bristol Myers Squibb (BMS) built around Bunsen, Schrödinger’s newly announced agentic AI co-scientist. While the term “AI co-scientist” can have varying definitions, Schrödinger is positioning Bunsen as a sort of execution engine for computational chemistry, including… ## [Diary of a Fruit Fly: The Peaches Are Excellent, the Dog Is Terrifying, and Hans Is a Murderer.](https://nutmegphantasy.substack.com/p/diary-of-a-fruit-fly-the-peaches) _2026-08-17 · Hans Casteels · The Oncology Underground_ By Hans Casteels ## [The Thirty Dollar Solution to the Hundred Thousand Dollar Problem](https://nutmegphantasy.substack.com/p/the-thirty-dollar-solution-to-the) _2026-08-17 · Hans Casteels · The Oncology Underground_ A Guest Essay for Erica Sell, who is grappling with the same questions I am grappling with. ## [How to safely combine cannabis oils such as THC and CBD with repurposed drugs in relation to different tumor types](https://oncologytruth.substack.com/p/how-to-safely-combine-cannabis-oils-122) _2026-08-16 · Repurposed Oncology · Repurposed Oncology_ Introduction on a new perspective on botanical compounds and liver traffic management ## [🔬 Latest pharma industry updates 👇](https://weeklybiopharmaupdates.substack.com/p/latest-pharma-industry-updates-afd) _2026-08-16 · Nicolas Schmitz · 🔬 Latest Pharma Industry Updates_ 🤝 Jazz Pharmaceuticals will acquire Actio Biosciences, Inc. for up to $1.3B, adding a rare epilepsy drug and expanding its neuroscience pipeline. ## [Anyone Else Feels This Way? I Am Sick of Being the Sick Person](https://nutmegphantasy.substack.com/p/anyone-else-feels-this-way-i-am-sick) _2026-08-16 · Hans Casteels · The Oncology Underground_ Hans With Cancer, Third Earl of Firmagon, Lord of the Hot Flash, Protector of the Urinal, Defender of the Questionable PSA. And I resent that. ## [The Cruelest Side Effect Is the Second Guess](https://nutmegphantasy.substack.com/p/the-cruelest-side-effect-is-the-second) _2026-08-15 · Hans Casteels · The Oncology Underground_ By Hans Casteels, second-guessing himself all the time ## [The turbo cancer mechanism after covid exposure as a comprehensive analysis of immune blockade and accelerated disease progression](https://oncologytruth.substack.com/p/the-turbo-cancer-mechanism-after) _2026-08-14 · Repurposed Oncology_ Introduction on a new perspective on host surveillance networks ## [My Wife Speaks Italian. Unfortunately, She Doesn’t Need Words.](https://nutmegphantasy.substack.com/p/my-wife-speaks-italian-unfortunately) _2026-08-14 · Hans Casteels · The Oncology Underground_ By Hans Casteels ## [FDA Approves Multiple Myeloma Combo Regimen](https://www.oncologynewscentral.com/drugs/info/fda-approves-combination-regimen-for-relapsed-or-refractory-multiple-myeloma) _2026-08-14 · ONC_ The FDA granted accelerated approval to iberdomide plus daratumumab and hyaluronidase-fihj and dexamethasone for adults with relapsed multiple myeloma. ## [Tumour microenvironment factors may influence cancer progression and response to tamoxifen (Nolvadex) in patients with estrogen receptor-positive and human epidermal growth factor receptor 2 breast cancer](https://www.2minutemedicine.com/tumour-microenvironment-factors-may-influence-cancer-progression-and-response-to-tamoxifen-nolvadex-in-patients-with-estrogen-receptor-positive-and-human-epidermal-growth-factor-receptor-2-breast-ca/) _2026-08-13 · Alex Xiang · Oncology | 2 Minute Medicine_ 1. In patients with estrogen receptor (ER)+ and human epidermal growth factor receptor 2 (HER2)- breast cancer, certain tumour microenvironments (TMEs) were associated with improved breast cancer progression and treatment response to tamoxifen (Nolvadex). Evidence Rating Level: 1 (Excellent) The TME of tumour, immune, and stromal cells varies depending on breast cancer estrogen receptor status.… ## [The 50 best-funded biotech companies of 2026](https://www.drugdiscoverytrends.com/the-50-best-funded-biotech-companies-of-2026/) _2026-08-13 · Brian Buntz · Drug Discovery and Development_ By one measure, Alphabet-controlled Isomorphic Labs would tower over every company on this list. The AI drug discovery company has raised $2.7 billion in external financing, including a $2.1 billion Series B announced in May. Its corporate structure, however, puts it outside our definition of an independent biotech startup: Alphabet still controls at least 75%… The post The 50 best-funded biotech… ## [New cell imaging method reveals hidden enzyme activity](https://www.drugdiscoverytrends.com/new-cell-imaging-method-reveals-hidden-enzyme-activity/) _2026-08-13 · Julia Rock-Torcivia · Drug Discovery and Development_ Negative biosensors have often been unusable because, as the sensors lose signal when activity is detected, regions of high enzyme activity can look identical to regions with no activity. Researchers at the University of Illinois Chicago have solved this problem with a new cell imaging method that allows scientists to see previously hidden enzyme activities by flipping the optical readout of… The… ## [HHS seeks nominees for vaccine advisory panel with $757K estimated annual cost after almost two years without a meeting](https://www.drugdiscoverytrends.com/hhs-seeks-nominees-for-vaccine-advisory-panel-with-757k-estimated-annual-cost-after-almost-two-years-without-a-meeting/) _2026-08-13 · Julia Rock-Torcivia · Drug Discovery and Development_ The Department of Health and Human Services (HHS) is soliciting nominations for appointment to the National Vaccine Advisory Committee (NVAC), the agency said in a notice published Wednesday. A renewed NVAC charter filed in July estimates the committee’s annual operating cost at $756,918 and calls for staff support equivalent to two full-time employees. The committee has not met since September… ## [Jeff Sharman, MD](https://www.oncologynewscentral.com/contributor/jeff-sharman) _2026-08-13 · ONC_ Jeff Sharman, MD, is the director of research at the Willamette Valley Cancer Institute as well as the medical director of hematology research for The US Oncology Network. ## [This week in MathOnco 379](https://thisweekmathonco.substack.com/p/this-week-in-mathonco-379) _2026-08-13 · Jeffrey West · This week in Mathematical Oncology_ Mathematical biomarkers ## [New Therapies Reshape ALK- and ROS1-Mutated NSCLC Care](https://www.oncologynewscentral.com/nsclc/targeted-therapies-are-reshaping-alk-and-ros1-mutated-nsclc-care) _2026-08-13 · ONC_ Sandip P. Patel, MD, shares which recent developments could affect clinical practice in ROS1- and ALK-positive non-small cell lung cancer. ## [Will FDA Follow EU in Approving Breast Cancer Drug?](https://www.oncologynewscentral.com/breast-cancer/will-the-fda-follow-the-eus-lead-on-camizestrant-in-breast-cancer) _2026-08-13 · ONC_ The European Union’s recent approval of camizestrant using the SERENA-6 switch strategy could strengthen the drug’s case with regulators in the United States. ## [The Hierarchy of Suffering](https://nutmegphantasy.substack.com/p/the-hierarchy-of-suffering) _2026-08-13 · Hans Casteels · The Oncology Underground_ By Hans Casteels ## [A health coaching intervention may improve blood pressure control in postpartum women](https://www.2minutemedicine.com/a-health-coaching-intervention-may-improve-blood-pressure-control-in-postpartum-women/) _2026-08-12 · Alex Xiang · Chronic Disease | 2 Minute Medicine_ 1. A health coaching intervention combined with self-measured blood pressure (SMBP) monitoring for postpartum women was associated with significantly greater engagement with primary care and significantly greater reductions in systolic and diastolic blood pressure (BP). Evidence Rating Level: 1 (Excellent) Hypertensive disorders of pregnancy (HDP) affect up to 16% of pregnancies in the United…