Chronic pain is reflected in the folds and grooves of the cerebral cortex

[ Surface-based morphometry workflow for ROI-wise cortical surface feature extraction. Surface atlases were mapped to individual surfaces using the spherical registration parameters obtained during surface processing. Surface-based measures (e.g., cortical thickness, sulcal depth) were then extracted for each ROI in native space. Credit: NeuroImage: Clinical (2026). DOI: 10.1016/j.nicl.2026.104023…