# neurology (blogs) — RSS Amplifier Recent posts from the 11 feeds in the RSS Amplifier directory that cover neurology. Page: Feed: --- ## [Positive psychotherapy may be similarly effective to traditional cognitive behavioural therapy for panic disorder](https://www.2minutemedicine.com/positive-psychotherapy-may-be-similarly-effective-to-traditional-cognitive-behavioural-therapy-for-panic-disorder/) _2026-08-21 · Paary Balakumar · 2 Minute Medicine_ 1. Positive Psychotherapy (PPT) produced anxiety and well-being outcomes statistically comparable to standard CBT, suggesting it may be a viable alternative for patients who do not respond to or prefer not to pursue traditional exposure-based treatment. 2. Both interventions demonstrated durable, clinically meaningful improvement sustained at three-month follow-up in an online group format… ## [Brain-predicted age difference may reliably predict dementia progression](https://www.2minutemedicine.com/brain-predicted-age-difference-may-reliably-predict-dementia-progression/) _2026-08-19 · Paary Balakumar · Neurology | 2 Minute Medicine_ 1. Brain-predicted age difference (brain-PAD) is a robust, reproducible predictor of dementia progression across two independent estimation methods, and it is most clinically useful in subjective cognitive decline, where it can help identify low-risk patients and reassure the “worried well,” rather than in mild cognitive impairment, where visual rating scales already capture most prognostically… ## [Diffusion-weighted imaging may aid in prognostication for intracerebral hemorrhage](https://www.2minutemedicine.com/diffusion-weighted-imaging-may-aid-in-prognostication-for-intracerebral-hemorrhage/) _2026-08-18 · Paary Balakumar · Neurology | 2 Minute Medicine_ 1. Diffusion-weighted imaging (DWI)-positive lesions are common after intracerebral hemorrhage (ICH) and serve as an independent biomarker of cerebral small vessel disease (cSVD) severity and worse 6-month functional outcome, supporting their potential use in prognostication and clinical trial patient selection. 2. The anatomical distribution of DWI-positive lesions may help distinguish cerebral… ## [A neurostimulation intervention may improve pain in patients with chronic low back pain](https://www.2minutemedicine.com/a-neurostimulation-intervention-may-improve-pain-in-patients-with-chronic-low-back-pain/) _2026-08-17 · Paary Balakumar · Neurology | 2 Minute Medicine_ 1. Restorative neurostimulation produces durable, clinically meaningful improvements in pain, disability, and quality of life at 5 years in real-world chronic mechanical low back pain patients. Evidence Rating Level: 3 (Average) This 5-year follow-up study evaluated restorative neurostimulation (ReActiv8) for chronic mechanical low back pain (CLBP) attributed to multifidus dysfunction. Restorative… ## [2 Minute Medicine Rewind August 17, 2026](https://www.2minutemedicine.com/2-minute-medicine-rewind-august-17-2026/) _2026-08-17 · Paary Balakumar · 2 Minute Medicine_ The impact of short-term reduction in hepatic triglycerides on vascular health in adults with or at risk of metabolic dysfunction-associated steatotic liver disease 1. Short-term dietary weight loss targeting hepatic fat reduction was associated with measurable improvements in arterial stiffness, endothelial function, and cardiovascular risk scores in MASLD patients. 2. These vascular improvements… ## [Melatonin use is associated with lower proportions of rapid eye movement sleep in children](https://www.2minutemedicine.com/melatonin-use-is-associated-with-lower-proportions-of-rapid-eye-movement-sleep-in-children/) _2026-08-14 · Alex Xiang · 2 Minute Medicine_ 1. In an observational study of pediatric patients, melatonin use may be associated with a decreased percentage of rapid eye movement (REM) sleep compared to melatonin nonusers. Evidence Rating Level: 2 (Good) Melatonin has been used by up to 19% of pediatric patients in the past 30 days. It is available without a prescription, and \[…\] The post Melatonin use is associated with lower proportions of… ## [Tumour microenvironment factors may influence cancer progression and response to tamoxifen (Nolvadex) in patients with estrogen receptor-positive and human epidermal growth factor receptor 2 breast cancer](https://www.2minutemedicine.com/tumour-microenvironment-factors-may-influence-cancer-progression-and-response-to-tamoxifen-nolvadex-in-patients-with-estrogen-receptor-positive-and-human-epidermal-growth-factor-receptor-2-breast-ca/) _2026-08-13 · Alex Xiang · 2 Minute Medicine_ 1. In patients with estrogen receptor (ER)+ and human epidermal growth factor receptor 2 (HER2)- breast cancer, certain tumour microenvironments (TMEs) were associated with improved breast cancer progression and treatment response to tamoxifen (Nolvadex). Evidence Rating Level: 1 (Excellent) The TME of tumour, immune, and stromal cells varies depending on breast cancer estrogen receptor status.… ## [A health coaching intervention may improve blood pressure control in postpartum women](https://www.2minutemedicine.com/a-health-coaching-intervention-may-improve-blood-pressure-control-in-postpartum-women/) _2026-08-12 · Alex Xiang · 2 Minute Medicine_ 1. A health coaching intervention combined with self-measured blood pressure (SMBP) monitoring for postpartum women was associated with significantly greater engagement with primary care and significantly greater reductions in systolic and diastolic blood pressure (BP). Evidence Rating Level: 1 (Excellent) Hypertensive disorders of pregnancy (HDP) affect up to 16% of pregnancies in the United… ## [Surgery is associated with an increased quality of life in women with endometriosis](https://www.2minutemedicine.com/surgery-is-associated-with-an-increased-quality-of-life-in-women-with-endometriosis/) _2026-08-11 · Alex Xiang · 2 Minute Medicine_ 1. In adult women with endometriosis, surgery was associated with an increased quality of life independent of their #Enzian classification. Evidence Rating Level: 2 (Good) Endometriosis affects 7-10% of women of reproductive age and has a heterogeneous presentation, ranging from superficial peritoneal implants to involvement of retroperitoneal structures. The wide range of symptoms associated with… ## [Bougie-guided and stylet-guided intubation may have similar success rate in the intubation of trauma patients](https://www.2minutemedicine.com/bougie-guided-and-stylet-guided-intubation-may-have-similar-success-rate-in-the-intubation-of-trauma-patients/) _2026-08-11 · Alex Xiang · 2 Minute Medicine_ 1. In critically injured trauma patients with difficult airways, there were no statistically significant differences in first-pass success between bougie-guided and stylet-guided intubation. Evidence Rating Level: 1 (Excellent) First-pass intubation failure during emergency airway management is associated with hypoxia, aspiration, hemodynamic instability, and cardiac arrest. This is particularly… ## [profullstack on Ko‑fi (Sponsored)](https://crawlproof.com/a/K4OOUj68JzQW) _2026-08-11 · **Sponsored**_ Open the creator's Ko‑fi page. ## [Joint fusion superior to watchful waiting for hallux rigidus](https://www.2minutemedicine.com/joint-fusion-superior-to-watchful-waiting-for-hallux-rigidus/) _2026-08-10 · Adrian Wong · 2 Minute Medicine_ 1. In this randomized controlled trial, arthrodesis significantly reduced walking-related pain compared with watchful waiting in adults aged 40 years or older with hallux rigidus. 2. Arthrodesis also improved pain at rest and was associated with lower analgesic use. Evidence Rating Level: 1 (Excellent) Study Rundown: Hallux rigidus, or osteoarthritis of the first metatarsophalangeal joint \[…\] The… ## [Antithrombotic agents may be effective in preventing migraine in patients with patent foramen ovale](https://www.2minutemedicine.com/antithrombotic-agents-may-be-effective-in-preventing-migraine-in-patients-with-patent-foramen-ovale/) _2026-08-07 · Siwen Liu · Neurology | 2 Minute Medicine_ 1. The antithrombotic agents aspirin, clopidogrel, and rivaroxaban were non-inferior to metoprolol for responder rate in participants with patent foramen ovale and migraine. Evidence Rating Level: 1 (Excellent) Patent foramen ovale (PFO) has been associated with migraine and has been suggested to involve a microembolic mechanism. Antithrombotic treatment has been proposed for migraine prevention… ## [Active surveillance is cost-effective compared with standard surgery among esophageal cancer patients with complete clinical response after neoadjuvant chemoradiotherapy](https://www.2minutemedicine.com/active-surveillance-is-cost-effective-compared-with-standard-surgery-among-esophageal-cancer-patients-with-complete-clinical-response-after-neoadjuvant-chemoradiotherapy/) _2026-08-06 · Siwen Liu · Chronic Disease | 2 Minute Medicine_ 1. Active surveillance was cost-effective over 5 years compared with standard surgery in patients with esophageal cancer and complete clinical response after neoadjuvant chemoradiotherapy. Evidence Rating Level: 1 (Excellent) Active surveillance for patients with esophageal cancer and a complete clinical response (CCR) after neoadjuvant chemoradiotherapy (nCRT) is noninferior to standard surgery… ## [Intraarterial dexamethasone may be effective for pain relief following uterine fibroid embolization](https://www.2minutemedicine.com/intraarterial-dexamethasone-may-be-effective-for-pain-relief-following-uterine-fibroid-embolization/) _2026-08-05 · Siwen Liu · Chronic Disease | 2 Minute Medicine_ 1. Intraarterial dexamethasone was associated with greater pain relief after uterine fibroid embolization compared with placebo. Evidence Rating Level: 1 (Excellent) Uterine fibroid embolization (UFE) is a minimally invasive treatment for symptomatic uterine fibroids, which are most common tumor of the female reproductive tract. However, a major limitation of UFE is acute postprocedural pain.… ## [Hematologic inflammatory indices may predict prognosis in younger patients with COVID-19 but not older patients](https://www.2minutemedicine.com/hematologic-inflammatory-indices-may-predict-prognosis-in-younger-patients-with-covid-19-but-not-older-patients/) _2026-08-04 · Siwen Liu · Chronic Disease | 2 Minute Medicine_ 1. Hematologic inflammatory indices in emergency department patients with COVID-19 showed an age-dependent prognostic performance for 30-day mortality, with systemic immune-inflammation index showing good discriminatory performance in patients \<65 years and poorer performance in patients \>65 years. Evidence Rating Level: 2 (Good) Hematologic markers derived from the complete blood count (CBC)… ## [Younger age and systemic metastases may independently predict survival among patients with choroidal metastases](https://www.2minutemedicine.com/younger-age-and-systemic-metastases-may-independently-predict-survival-among-patients-with-choroidal-metastases/) _2026-08-03 · Siwen Liu · Chronic Disease | 2 Minute Medicine_ 1. Younger age (\<59.6 years) and systemic metastases (\>1) were independent predictors of survival among patients with choroidal metastases. Evidence Rating Level: 2 (Good) Around 1–2% of all cancer patients develop intraocular metastases, with the choroid representing the primary site of metastatic involvement (90%). It is unclear how age and primary tumor type impact survival \[…\] The post Younger… ## [A digital mental health intervention may improve anxiety in breast cancer survivors](https://www.2minutemedicine.com/a-digital-mental-health-intervention-may-improve-anxiety-in-breast-cancer-survivors/) _2026-07-31 · Lori Lai · Psychiatry | 2 Minute Medicine_ 1. Among a large cohort of breast cancer survivors, those who participated in digital mental health treatment reported a reduction in symptoms of anxiety, with additional human coaching associated with a reduction in depression. Evidence Rating Level: 1 (Excellent) Almost 50% of all women suffering from advanced breast cancer experience significant anxiety and depression within \[…\] The post A… ## [A cognitive rehabilitation program may improve cognitive performance in patients with long COVID](https://www.2minutemedicine.com/a-cognitive-rehabilitation-program-may-improve-cognitive-performance-in-patients-with-long-covid/) _2026-07-28 · Lori Lai · Psychiatry | 2 Minute Medicine_ 1. In a multicenter, single-blind, randomized clinical trial, participation in a cognitive rehabilitation program improved goal attainment and cognitive test scores in patients suffering from Long COVID-related cognitive dysfunction. Evidence Rating Level: 1 (Excellent) Long COVID is defined as a chronic condition that occurs following the infection of COVID-19, present for at least 3 months \[…\]… ## [Medical or procedural abortion may not increase risk of psychotropic medication use after five years](https://www.2minutemedicine.com/medical-or-procedural-abortion-may-not-increase-risk-of-psychotropic-medication-use-after-five-years/) _2026-07-27 · Lori Lai · Psychiatry | 2 Minute Medicine_ 1. Among a Danish population-based cohort study, increased initiation of psychotropic medication in the first year following both medical and procedural methods of abortion were found, with decreased risk of initiation of psychotropic medication within five or more years following both medical and procedural abortions. Evidence Rating Level: 2 (Good) There is limited research on \[…\] The post… ## [A medical care at home program following hospitalization with acute decompensated heart failure may offer a safe and effective alternative to continued hospitalization](https://www.2minutemedicine.com/a-medical-care-at-home-program-following-hospitalization-with-acute-decompensated-heart-failure-may-offer-a-safe-and-effective-alternative-to-continued-hospitalization/) _2026-07-24 · Simon Pan · Cardiology | 2 Minute Medicine_ 1. Following hospitalization for acute decompensated heart failure (HF), there was no difference in all-cause readmissions and mortality between patients treated with an advanced medical care at home (AMCAH) program compared with brick-and-mortar (BAM) hospitalization. Evidence Rating Level: 2 (Good) Acute hospital care at home programs have seen a dramatic increase in implementation since the \[…\]… ## [Real SIMs for AI Agents (Sponsored)](https://crawlproof.com/a/URLUTynT1f7l) _2026-07-24 · **Sponsored**_ Pass 2FA and verifications with real carrier numbers via our API. ## [Catheter ablation within 1 year of atrial fibrillation diagnosis is associated with reduced risk of recurrence](https://www.2minutemedicine.com/catheter-ablation-within-1-year-of-atrial-fibrillation-diagnosis-is-associated-with-reduced-risk-of-recurrence/) _2026-07-24 · Simon Pan · Cardiology | 2 Minute Medicine_ 1. Patients with atrial fibrillation (AF) treated with catheter ablation 1 to 4 years after AF diagnosis had a 48% higher chance of AF recurrence compared to those treated within 1 year. 2. Patients with atrial fibrillation (AF) treated with catheter ablation 5 years or greater after AF diagnosis had a 110% higher chance of \[…\] The post Catheter ablation within 1 year of atrial fibrillation… ## [Epidural analgesia in labour is not associated with adverse neonatal health outcomes](https://www.2minutemedicine.com/epidural-analgesia-in-labour-is-not-associated-with-adverse-neonatal-health-outcomes/) _2026-07-23 · Simon Pan · Neurology | 2 Minute Medicine_ 1. Epidural analgesia in labour is not associated with significant risk of neonatal neurological morbidity, neonatal morbidity or mortality. Evidence Rating Level: 2 (Good) Epidural analgesia during labour is regarded as the most effective form of pain control, which is important given that poor pain control may lead to physiological stress in mothers with important \[…\] The post Epidural analgesia… ## [2MM: AI Roundup: NHS England expands Microsoft Copilot nationwide, ARPA-H advances autonomous cardiovascular AI, FDA advisors back Moderna’s mRNA influenza vaccine, and UpDoc earns first clearance for a patient-facing large language model](https://www.2minutemedicine.com/2mm-ai-roundup-food-and-drug-administration-reviews-liver-injury-prediction-tool-joint-commission-launches-healthcare-artificial-intelligence-certification-governance-playbooks-aim-to-standardize-2/) _2026-07-20 · Deepti Shroff · Pediatrics | 2 Minute Medicine_ NHS England is rolling out Microsoft Copilot to 505,000 clinicians after a 30,000-person trial saved nearly an hour of admin time per day Recently, NHS England announced it will deploy Microsoft 365 Copilot to 505,000 clinicians and support staff, following a nine-month pilot across 30,000 workers at 90 NHS organizations. The headline result from that \[…\] The post 2MM: AI Roundup: NHS England… ## [A chemical denervation intervention may be safe and effective for pain management in avascular necrosis of the hip](https://www.2minutemedicine.com/a-chemical-denervation-intervention-may-be-safe-and-effective-for-pain-management-in-avascular-necrosis-of-the-hip/) _2026-07-16 · Paary Balakumar · Neurology | 2 Minute Medicine_ 1. Chemical neurolysis of the anterior hip capsular branches appears to be a safe and effective analgesic option for AVN-related hip pain refractory to conservative management, with durable benefit in a subset of patients through 6 months. Evidence Rating Level: 3 (Average) Avascular necrosis (AVN) of the hip frequently causes refractory pain that persists despite \[…\] The post A chemical… ## [Spinal instability may be the primary cause of pain in sacral metastases as opposed to neurologic compromise](https://www.2minutemedicine.com/spinal-instability-may-be-the-primary-cause-of-pain-in-sacral-metastases-as-opposed-to-neurologic-compromise/) _2026-07-14 · Paary Balakumar · Neurology | 2 Minute Medicine_ 1. Although neurological symptoms (motor deficits, sensory impairment) were more frequent in patients with sitting-related sacral pain on univariate comparison, this association did not hold in multivariable analysis (aOR 0.83, 95% CI 0.21–2.95, p=0.780), indicating spinal instability—not neurological compromise—was the primary driver of this pain. 2. Patients with sitting-related sacral pain had… ## [Infection risk with infliximab (Remicade) and adalimumab (Humira) is similar in pediatric inflammatory bowel disease](https://www.2minutemedicine.com/infection-risk-with-infliximab-remicade-and-adalimumab-humira-is-similar-in-pediatric-inflammatory-bowel-disease/) _2026-07-14 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. Among children with inflammatory bowel disease, there were no significant differences in serious or outpatient infection risk between initiating infliximab (Remicade) and adalimumab (Humira). Evidence Rating Level: 2 (Good) Study Rundown: Pediatric Inflammatory Bowel Disease (IBD) includes Crohn disease (CD), ulcerative colitis (UC), and IBD-unclassified (IBD-U), and its prevalence is… ## [Glucosamine Linked to Faster Alzheimer’s Progression in Patients with Mild Cognitive Impairment](https://www.2minutemedicine.com/glucosamine-linked-to-faster-alzheimers-progression-in-patients-with-mild-cognitive-impairment/) _2026-07-10 · Deepti Shroff · Psychiatry | 2 Minute Medicine_ 1. University of Florida researchers found that glucosamine, the popular joint supplement taken by tens of millions of older Americans, is associated with a 25% higher likelihood of progressing from mild cognitive impairment to Alzheimer’s disease. 2. The proposed mechanism is biochemically plausible: glucosamine is a sugar-related molecule that crosses the blood-brain barrier and appears \[…\] The… ## [ITI Treatment Guide – Volume 9 Implant Therapy in the Geriatric Patient (2016) F. Müller](https://unitedvrg.com/2026/07/08/iti-treatment-guide-volume-9-implant-therapy-in-the-geriatric-patient-2016-f-muller-2/) _2026-07-08 · eric · UnitedVRG_ This volume of the ITI Treatment Guide provides a step-by-step guide and consensus recommendations for implant therapy specifically tailored for the geriatric patient, based on conclusions from ITI Consensus Conferences. ## [Basic and Clinical Science Course – Section 2 Fundamentals and Principles of Ophthalmology (2018) American Academy of Ophthalmology](https://unitedvrg.com/2026/07/08/basic-and-clinical-science-course-section-2-fundamentals-and-principles-of-ophthalmology-2018-american-academy-of-ophthalmology/) _2026-07-08 · eric · UnitedVRG_ This volume is part of the Basic and Clinical Science Course (BCSC) designed to increase the physician’s ophthalmic knowledge through study and review. It provides continuing medical education (CME) focusing on the foundational principles of ophthalmology. ## [Handouts on Glasses in Kids – Pediatric Refraction and Spectacle Prescription (2024) Dr. ElGhonemy](https://unitedvrg.com/2026/07/08/handouts-on-glasses-in-kids-pediatric-refraction-and-spectacle-prescription-2024-dr-elghonemy/) _2026-07-08 · eric · UnitedVRG_ Essential guidance material for pediatric ophthalmologists and optometrists regarding the diagnosis and management of refractive errors in children and the correct prescription of spectacle lenses. ## [Stop CI/CD & Supply-Chain Attacks (Sponsored)](https://crawlproof.com/a/IR4KZUA6HFrT) _2026-07-08 · **Sponsored**_ Per-PR: 17 CI/CD checks and package malware scans with inline Check Run findings. ## [Cardiac Physiology Hemodynamics – Analysis of Stroke Volume, Ejection Fraction, Cardiac Work, and Fick’s Principle (2024) Dr. Elias K. Harrington](https://unitedvrg.com/2026/07/08/cardiac-physiology-hemodynamics-analysis-of-stroke-volume-ejection-fraction-cardiac-work-and-ficks-principle-2024-dr-elias-k-harrington/) _2026-07-08 · eric · UnitedVRG_ This text provides a foundational overview of cardiovascular hemodynamics, covering the determinants of cardiac output (stroke volume and heart rate), definitions of end-systolic and end-diastolic volumes, calculation of ejection fraction, and methods for measuring cardiac output (Fick's principle). It extensively analyzes cardiac work (volume vs. pressure work) and relates heart mechanics to the… ## [Basis of Pediatrics – Principles of Pediatric Medicine and Neonatal Care (2024) Elizabeth K. Chen, MD](https://unitedvrg.com/2026/07/08/basis-of-pediatrics-principles-of-pediatric-medicine-and-neonatal-care-2024-elizabeth-k-chen-md/) _2026-07-08 · eric · UnitedVRG_ This comprehensive 15th edition serves as the essential foundational text for medical students and residents entering the field of pediatric medicine. It covers core topics from normal child development and adolescent health to the diagnosis and evidence-based management of common and complex pediatric diseases, including neonatal critical care protocols. ## [PICU Protocol of EHA – Egyptian Clinical Practice Protocols in Pediatric Intensive Care Units for Egypt Healthcare Authority (2022) Prof. Dr. Hanan Ibrahim](https://unitedvrg.com/2026/07/08/picu-protocol-of-eha-egyptian-clinical-practice-protocols-in-pediatric-intensive-care-units-for-egypt-healthcare-authority-2022-prof-dr-hanan-ibrahim/) _2026-07-08 · eric · UnitedVRG_ Protocols and guidelines developed to unify and standardize the delivery of high-quality healthcare in Pediatric Intensive Care Units (PICUs) for the Egypt Healthcare Authority (EHA). ## [Clinical Pathophysiology Made Ridiculously Simple – WITH INTERACTIVE DIFFERENTIAL DIAGNOSIS CD (2007) Aaron Berkowitz](https://unitedvrg.com/2026/07/08/clinical-pathophysiology-made-ridiculously-simple-with-interactive-differential-diagnosis-cd-2007-aaron-berkowitz/) _2026-07-08 · eric · UnitedVRG_ A simplified guide to the clinical pathophysiology of all major organ systems, including cardiovascular, pulmonary, renal, GI, endocrine, hematologic, nervous, and reproductive systems, presented in an easy-to-understand format. ## [MCQ in Microbiology – Multiple Choice Questions in Microbiology (2008) Unknown Author](https://unitedvrg.com/2026/07/08/mcq-in-microbiology-multiple-choice-questions-in-microbiology-2008-unknown-author/) _2026-07-08 · eric · UnitedVRG_ This book contains multiple choice questions (MCQs) designed to help students review their knowledge of Microbiology acquired through standard textbooks. It is primarily meant for students preparing for PG competitive examinations (such as USMLE, GATE, AFMC, AIIMS) and is essential for students of Medicine, Pharmacy, Dentistry, and Nursing, serving as a self-assessment opportunity. ## [Alzheimer’s Disease – Methods and Protocols (2023) Jerold Chun](https://unitedvrg.com/2026/07/08/alzheimers-disease-methods-and-protocols-2023-jerold-chun/) _2026-07-08 · eric · UnitedVRG_ This volume provides readily-reproducible, step-by-step research protocols and methodologies focused on Alzheimer's Disease. Part of the Methods in Molecular Biology series, it offers detailed procedures, material lists, and helpful notes, tips, and troubleshooting advice. ## [Targeting Oral Cancer (2016) Andrew M. Fribley](https://unitedvrg.com/2026/07/07/targeting-oral-cancer-2016-andrew-m-fribley/) _2026-07-07 · eric · UnitedVRG_ This book explores the dynamic epidemiology, staging, surgical management, and current treatment modalities (including chemotherapy) for oral and pharyngeal cancer and Head and Neck Squamous Cell Carcinoma (HNSCC). It also details the molecular progression, role of cancer stem cells, and emerging biomarkers derived from key processes of cancerogenesis. ## [Dietary habits are associated with dementia risk in patients with Alzheimer’s pathology](https://www.2minutemedicine.com/dietary-habits-are-associated-with-dementia-risk-in-patients-with-alzheimers-pathology/) _2026-07-03 · Siwen Liu · Neurology | 2 Minute Medicine_ 1. Greater adherence to a dietary pattern with lower inflammatory potential was associated with lower dementia risk among individuals with Alzheimer’s pathology and broader neurobiological risk. Evidence Rating Level: 2 (Good) Alzheimer’s disease (AD) is a leading cause of dementia. Evidence suggests that nutrients, foods, and dietary patterns may mitigate AD. However, it is unclear \[…\] The post… ## [The association between parental and offspring body mass index may be due to genetic confounding](https://www.2minutemedicine.com/the-association-between-parental-and-offspring-body-mass-index-may-be-due-to-genetic-confounding/) _2026-06-30 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. The association between parental body mass index (BMI) and offspring BMI from age 6 months to 8 years may primarily be due to genetic confounding. Evidence Rating Level: 2 (Good) Although parental body mass index (BMI) has been associated with offspring adiposity in childhood, the mechanisms behind this relationship remain unclear. This study thus \[…\] The post The association between parental… ## [The best possible](http://wordridden.com/post/1084) _2026-06-24 · WordRidden_ I think I may have had the perfect swim today. We’re in the middle of a brutal heatwave, and the only saving grace is that I have the time and ability to cool down with a swim every day. So I went down to the beach this morning with the aim of swimming early-ish and avoiding the worst of the heat. I didn’t entirely succeed because it was already about 30C/86F at 10 a.m. The water, though, was… ## [Recombinant Zoster Vaccination May Reduce Dementia Risk in Older Adults](https://www.2minutemedicine.com/recombinant-zoster-vaccination-may-reduce-dementia-risk-in-older-adults/) _2026-06-15 · Adrian Wong · Neurology | 2 Minute Medicine_ 1. In this target trial emulation, receipt of the recombinant zoster vaccine (RZV) was associated with a reduced risk of dementia among older adults admitted to skilled nursing facilities. 2. The association was more pronounced among women and among individuals who had not previously received the live attenuated herpes zoster vaccine. Evidence Rating Level: 2 \[…\] The post Recombinant Zoster… ## [2MM: AI Roundup: Food and Drug Administration reviews liver injury prediction tool, Joint Commission launches healthcare artificial intelligence certification, governance playbooks aim to standardize adoption, and pediatric hospitals bring generative tools to the frontline](https://www.2minutemedicine.com/2mm-ai-roundup-food-and-drug-administration-reviews-liver-injury-prediction-tool-joint-commission-launches-healthcare-artificial-intelligence-certification-governance-playbooks-aim-to-standardize/) _2026-06-15 · Deepti Shroff · Pediatrics | 2 Minute Medicine_ Food and Drug Administration reviews artificial intelligence tool for liver injury prediction The Food and Drug Administration (FDA) is reviewing an artificial intelligence based drug development tool designed to predict drug induced liver injury, one of the more stubborn safety problems in clinical development. The agency’s Center for Drug Evaluation and Research accepted a letter \[…\] The post… ## [Children conceived through infertility treatments may have similar growth compared to naturally conceived children](https://www.2minutemedicine.com/children-conceived-through-infertility-treatments-may-have-similar-growth-compared-to-naturally-conceived-children/) _2026-06-11 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. After accounting for plurality, children conceived through infertility treatments showed similar growth trajectories to those conceived naturally. Evidence Rating Level: 2 (Good) Compared to children conceived naturally, children conceived through medically assisted reproduction (MAR) may experience different birth outcomes and growth patterns. However, evidence on long-term growth trajectories… ## [Two scores for risk stratification of adults presenting with syncope may be effective at identifying those with low risk](https://www.2minutemedicine.com/two-scores-for-risk-stratification-of-adults-presenting-with-syncope-may-be-effective-at-identifying-those-with-low-risk/) _2026-05-29 · Alex Xiang · Cardiology | 2 Minute Medicine_ 1. The Canadian Syncope Risk Score (CSRS) and FAINT score are effective at identifying which adult patients presenting to the emergency department (ED) are at low risk for short-term adverse outcomes. Evidence Rating Level: 2 (Good) Syncope and presyncope account for 2-3% of all ED visits, with approximately 10% of these patients having serious underlying \[…\] The post Two scores for risk… ## [A novel therapy targeting γ-aminobutyric acid is safe and may be effective in major depressive disorder](https://www.2minutemedicine.com/a-novel-therapy-targeting-%ce%b3-aminobutyric-acid-is-safe-and-may-be-effective-in-major-depressive-disorder/) _2026-05-27 · Alex Xiang · Psychiatry | 2 Minute Medicine_ 1. H3-10353, a novel γ-aminobutyric acid (GABA) positive allosteric modulator, is safe and well-tolerated in healthy patients and those with major depressive disorder (MDD), and demonstrated some therapeutic benefits in a phase 1 clinical trial. Evidence Rating Level: 1 (Excellent) Although there are numerous classes of medications for depression, these treatments result in remission in \[…\] The… ## [Selective serotonin reuptake inhibitors may reduce risk of total joint arthroplasty in osteoarthritis](https://www.2minutemedicine.com/selective-serotonin-reuptake-inhibitors-may-reduce-risk-of-total-joint-arthroplasty-in-osteoarthritis/) _2026-05-21 · Paary Balakumar · Psychiatry | 2 Minute Medicine_ 1. Initiation of centrally acting analgesics in patients with osteoarthritis (OA) was associated with a higher long-term risk of total joint arthroplasty compared with SSRI initiation. 2. Management of comorbid depression may play an important role in OA symptom progression and surgical outcomes, potentially exceeding the benefit of centrally mediated analgesic effects alone. Evidence Rating \[…\]… ## [Adverse pregnancy outcomes is associated with worse offspring cardiovascular health in early adulthood](https://www.2minutemedicine.com/adverse-pregnancy-outcomes-is-associated-with-worse-offspring-cardiovascular-health-in-early-adulthood/) _2026-05-18 · Siwen Liu · Cardiology | 2 Minute Medicine_ 1. Exposure to adverse pregnancy outcomes, particularly hypertensive disorders of pregnancy, was associated with worse cardiovascular health and early arterial injury among offspring in early adulthood. Evidence Rating Level: 2 (Good) Study Rundown: Adverse pregnancy outcomes (APOs) have been associated with long-term maternal cardiovascular health (CVH). However, research on the role of APOs in… ## [Resuscitative endovascular balloon occlusion of the aorta may not improve outcomes in adults with non-traumatic out-of-hospital cardiac arrest](https://www.2minutemedicine.com/resuscitative-endovascular-balloon-occlusion-of-the-aorta-may-not-improve-outcomes-in-adults-with-non-traumatic-out-of-hospital-cardiac-arrest/) _2026-05-14 · Alex Xiang · Cardiology | 2 Minute Medicine_ 1. Resuscitative endovascular balloon occlusion of the aorta (REBOA) as an adjunct to advanced life support (ALS) does not improve rates of return of spontaneous circulation (ROSC) in adult patients with non-traumatic out-of-hospital cardiac arrest (OHCA). Evidence Rating Level: 1 (Excellent) OHCA remains associated with extremely high mortality, with most patients not achieving ROSC, and \[…\] The… ## [Use of selective serotonin reuptake inhibitors guided by pharmacogenetic testing may improve treatment response in depression](https://www.2minutemedicine.com/use-of-selective-serotonin-reuptake-inhibitors-guided-by-pharmacogenetic-testing-may-improve-treatment-response-in-depression/) _2026-05-13 · Alex Xiang · Psychiatry | 2 Minute Medicine_ 1. Genotype-guided prescribing of selective serotonin reuptake inhibitors (SSRIs) may improve treatment response in children and adults with depression. Evidence Rating Level: 1 (Excellent) Although SSRIs are the most prescribed pharmacotherapy for depression, discontinuation rates remain high, with some studies reporting up to 50% discontinuation due to ineffectiveness or adverse effects.… ## [Maternal use of benzodiazepines and non-benzodiazepine hypnotics is not associated with increased risk of psychiatric](https://www.2minutemedicine.com/maternal-use-of-benzodiazepines-and-non-benzodiazepine-hypnotics-is-not-associated-with-increased-risk-of-psychiatric/) _2026-05-06 · Siwen Liu · Psychiatry | 2 Minute Medicine_ 1. Maternal use of benzodiazepines or non-benzodiazepine hypnotics (Z-hypnotics) during pregnancy was not associated with an increased risk of psychiatric disorders in offspring after controlling for shared familial factors. Evidence Rating Level: 2 (Good) Benzodiazepines and non-benzodiazepine hypnotics (Z-hypnotics) are frequently prescribed drugs among pregnant women who commonly experience…