The Xylazine Crisis: Orthopaedics at the Frontline of an Evolving Epidemic

Xylazine, a veterinary sedative, has increasingly been found as an adulterant in illicit fentanyl supplies across the USA. This combination has led to severe necrotic skin wounds among users, particularly in the Philadelphia region, posing significant challenges for patients and healthcare providers. As these frequently exhibit as extremity wounds, orthopaedic surgeons are amongst those involved…