Methylcobalamin: Finally, Some Evidence

by Jack Norris, Registered Dietitian Vegan dietitians have typically recommended the cyanocobalamin form of vitamin B12 for vegans; it’s well-studied, stable, and inexpensive. The coenzyme forms, methylcobalamin and adenosylcobalamin, have been heavily marketed but poorly studied, with typical recommendations of 1,000 µg/day based more on caution than evidence. A 2026 randomized trial (MATCOBIND)…