Disruption of Serum Selenium and Chromium Homeostasis in Insulin Resistance

Background: Insulin resistance (IR) is a significant metabolic abnormality that occurs prior to the onset of T2DM and is related to oxidative stress and micronutrient imbalance. Selenium (Se) and chromium (Cr) are trace elements that have important functions in the body, including as antioxidants and in regulating insulin action; however, the relationships between these trace elements and IR…