# inflammatory bowel disease (blogs) — RSS Amplifier Recent posts from the 3 feeds in the RSS Amplifier directory that cover inflammatory bowel disease. Page: Feed: --- ## [Melatonin use is associated with lower proportions of rapid eye movement sleep in children](https://www.2minutemedicine.com/melatonin-use-is-associated-with-lower-proportions-of-rapid-eye-movement-sleep-in-children/) _2026-08-14 · Alex Xiang · Pediatrics | 2 Minute Medicine_ 1. In an observational study of pediatric patients, melatonin use may be associated with a decreased percentage of rapid eye movement (REM) sleep compared to melatonin nonusers. Evidence Rating Level: 2 (Good) Melatonin has been used by up to 19% of pediatric patients in the past 30 days. It is available without a prescription, and \[…\] The post Melatonin use is associated with lower proportions of… ## [Hematologic inflammatory indices may predict prognosis in younger patients with COVID-19 but not older patients](https://www.2minutemedicine.com/hematologic-inflammatory-indices-may-predict-prognosis-in-younger-patients-with-covid-19-but-not-older-patients/) _2026-08-04 · Siwen Liu · Infectious Disease | 2 Minute Medicine_ 1. Hematologic inflammatory indices in emergency department patients with COVID-19 showed an age-dependent prognostic performance for 30-day mortality, with systemic immune-inflammation index showing good discriminatory performance in patients \<65 years and poorer performance in patients \>65 years. Evidence Rating Level: 2 (Good) Hematologic markers derived from the complete blood count (CBC)… ## [New Mexico measles outbreak associated with significant costs](https://www.2minutemedicine.com/new-mexico-measles-outbreak-associated-with-significant-costs/) _2026-08-02 · Adrian Wong · Infectious Disease | 2 Minute Medicine_ 1. In this cost analysis, the 2025 measles outbreak in New Mexico was estimated to impose a societal economic burden of $5.4 million, equivalent to approximately $53,500 per case. 2. Public health response activities accounted for the majority of costs, with more than $2 million devoted to vaccination-related efforts aimed at controlling the outbreak. Evidence \[…\] The post New Mexico measles… ## [Praziquantel (Biltricide) is associated with higher cure rate than albendazole (Zentel) in the treatment of clonorchiasis](https://www.2minutemedicine.com/praziquantel-biltricide-is-associated-with-higher-cure-rate-than-albendazole-zentel-in-the-treatment-of-clonorchiasis/) _2026-07-31 · Alex Xiang · Infectious Disease | 2 Minute Medicine_ 1. In the treatment of Clonorchis sinensis, albendazole (Zentel) demonstrates a high egg reduction rate but a significantly lower cure rate compared to praziquantel (Biltricide). Evidence Rating Level: 1 (Excellent) Study Rundown: Clonorchiasis is caused by infection with Clonorchis sinensis, a helminth parasite, and can lead to significant morbidities, including cholelithiasis, cholangitis,… ## [A cognitive rehabilitation program may improve cognitive performance in patients with long COVID](https://www.2minutemedicine.com/a-cognitive-rehabilitation-program-may-improve-cognitive-performance-in-patients-with-long-covid/) _2026-07-28 · Lori Lai · Infectious Disease | 2 Minute Medicine_ 1. In a multicenter, single-blind, randomized clinical trial, participation in a cognitive rehabilitation program improved goal attainment and cognitive test scores in patients suffering from Long COVID-related cognitive dysfunction. Evidence Rating Level: 1 (Excellent) Long COVID is defined as a chronic condition that occurs following the infection of COVID-19, present for at least 3 months \[…\]… ## [Epidural analgesia in labour is not associated with adverse neonatal health outcomes](https://www.2minutemedicine.com/epidural-analgesia-in-labour-is-not-associated-with-adverse-neonatal-health-outcomes/) _2026-07-23 · Simon Pan · Pediatrics | 2 Minute Medicine_ 1. Epidural analgesia in labour is not associated with significant risk of neonatal neurological morbidity, neonatal morbidity or mortality. Evidence Rating Level: 2 (Good) Epidural analgesia during labour is regarded as the most effective form of pain control, which is important given that poor pain control may lead to physiological stress in mothers with important \[…\] The post Epidural analgesia… ## [Cefazolin non-inferior to penicillins for methicillin-susceptible Staphylococcus aureus bacteremia](https://www.2minutemedicine.com/cefazolin-non-inferior-to-penicillins-for-methicillin-susceptible-staphylococcus-aureus-bacteremia/) _2026-07-23 · Zhenyu Li · Infectious Disease | 2 Minute Medicine_ 1. In this international randomized controlled trial of adults with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia, cefazolin was noninferior to antistaphylococcal penicillins for 90-day mortality. 2. Cefazolin was also associated with fewer adverse events, particularly lower rates of acute kidney injury and treatment discontinuation due to toxicity. Evidence Rating Level: 1… ## [Novel antifungal shows promise for patients with refractory disseminated coccidioidomycosis](https://www.2minutemedicine.com/novel-antifungal-shows-promise-for-patients-with-refractory-disseminated-coccidioidomycosis/) _2026-07-20 · Adrian Wong · Infectious Disease | 2 Minute Medicine_ 1. In this single-group, open-label trial, olorofim was associated with a complete or partial clinical response in over 75% of patients with disseminated coccidioidomycosis (DCM) and limited or no treatment options. 2. Clinical success rates were highest among patients without central nervous system (CNS) infection. Evidence Rating Level: 2 (Good) Study Rundown: Every year, thousands \[…\] The post… ## [2MM: AI Roundup: NHS England expands Microsoft Copilot nationwide, ARPA-H advances autonomous cardiovascular AI, FDA advisors back Moderna’s mRNA influenza vaccine, and UpDoc earns first clearance for a patient-facing large language model](https://www.2minutemedicine.com/2mm-ai-roundup-food-and-drug-administration-reviews-liver-injury-prediction-tool-joint-commission-launches-healthcare-artificial-intelligence-certification-governance-playbooks-aim-to-standardize-2/) _2026-07-20 · Deepti Shroff · Pediatrics | 2 Minute Medicine_ NHS England is rolling out Microsoft Copilot to 505,000 clinicians after a 30,000-person trial saved nearly an hour of admin time per day Recently, NHS England announced it will deploy Microsoft 365 Copilot to 505,000 clinicians and support staff, following a nine-month pilot across 30,000 workers at 90 NHS organizations. The headline result from that \[…\] The post 2MM: AI Roundup: NHS England… ## [Infection risk with infliximab (Remicade) and adalimumab (Humira) is similar in pediatric inflammatory bowel disease](https://www.2minutemedicine.com/infection-risk-with-infliximab-remicade-and-adalimumab-humira-is-similar-in-pediatric-inflammatory-bowel-disease/) _2026-07-14 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. Among children with inflammatory bowel disease, there were no significant differences in serious or outpatient infection risk between initiating infliximab (Remicade) and adalimumab (Humira). Evidence Rating Level: 2 (Good) Study Rundown: Pediatric Inflammatory Bowel Disease (IBD) includes Crohn disease (CD), ulcerative colitis (UC), and IBD-unclassified (IBD-U), and its prevalence is… ## [Chovy's Blog: Agentic Coding (Sponsored)](https://crawlproof.com/a/i7miitChjZr9) _2026-07-14 · **Sponsored**_ Personal posts on agentic coding, moshcode CLI, and security findings. ## [Chronic Wasting Disease Spreads Silently in Symptom-Free Animals, Raising Questions About Long-Term Human Risk](https://www.2minutemedicine.com/chronic-wasting-disease-spreads-silently-in-symptom-free-animals-raising-questions-about-long-term-human-risk/) _2026-07-14 · Deepti Shroff · Infectious Disease | 2 Minute Medicine_ 1. A University of Calgary study published in Science Advances this month found that chronic wasting disease can spread silently in animals with no clinical symptoms, and demonstrated limited but detectable cross-species prion transmission in nonhuman primate models. 2. There are no confirmed human cases, but the expanding geographic footprint of the disease in wild \[…\] The post Chronic Wasting… ## [The Gut Health Supplement Industry Has Outrun the Science, Researchers Say](https://www.2minutemedicine.com/the-gut-health-supplement-industry-has-outrun-the-science-researchers-say/) _2026-07-13 · Deepti Shroff · Gastroenterology | 2 Minute Medicine_ 1. A June 2026 NPR investigation found the commercial gut microbiome market has run far ahead of what the science actually supports, with researchers pointing out that there is no agreed-upon definition of a healthy microbiome and that most DTC testing products are not held to diagnostic standards. 2. What the evidence does support is \[…\] The post The Gut Health Supplement Industry Has Outrun the… ## [Carvedilol linked to lower cirrhosis complication risk](https://www.2minutemedicine.com/carvedilol-linked-to-lower-cirrhosis-complication-risk/) _2026-07-06 · Adrian Wong · Gastroenterology | 2 Minute Medicine_ 1. In this retrospective cohort study, carvedilol was associated with a lower risk of major liver decompensation compared with nadolol and propranolol. 2. Carvedilol was also associated with lower risks of individual decompensation outcomes, including ascites, spontaneous bacterial peritonitis (SBP), and hepatorenal syndrome (HRS). Evidence Rating Level: 2 (Good) Study Rundown: Nonselective… ## [The association between parental and offspring body mass index may be due to genetic confounding](https://www.2minutemedicine.com/the-association-between-parental-and-offspring-body-mass-index-may-be-due-to-genetic-confounding/) _2026-06-30 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. The association between parental body mass index (BMI) and offspring BMI from age 6 months to 8 years may primarily be due to genetic confounding. Evidence Rating Level: 2 (Good) Although parental body mass index (BMI) has been associated with offspring adiposity in childhood, the mechanisms behind this relationship remain unclear. This study thus \[…\] The post The association between parental… ## [Male sex and hispanic ethnicity are associated with increased risk of early-onset colorectal cancer](https://www.2minutemedicine.com/male-sex-and-hispanic-ethnicity-are-associated-with-increased-risk-of-early-onset-colorectal-cancer/) _2026-06-29 · Siwen Liu · Gastroenterology | 2 Minute Medicine_ 1. Male sex and Hispanic ethnicity were associated with increased risk of early-onset colorectal cancer (EOCRC). 2. Among females, higher birthweight and older paternal age were associated with increased EOCRC risk. 3. Among males, having a foreign-born mother was associated with lower EOCRC risk. Evidence Rating Level: 3 (Average) EOCRC is defined as CRC diagnosed \[…\] The post Male sex and… ## [Concomitant COVID-19 and influenza vaccination not linked to increased adverse events](https://www.2minutemedicine.com/concomitant-covid-19-and-influenza-vaccination-not-linked-to-increased-adverse-events/) _2026-06-29 · Adrian Wong · Infectious Disease | 2 Minute Medicine_ 1. In this target trial emulation, same-day administration of COVID-19 and influenza vaccines was not associated with an increased risk of adverse events. 2. No differences in adverse event risk were observed across the bivalent, XBB-adapted, and KP-adapted COVID-19 vaccine formulations. Evidence Rating Level: 2 (Good) Study Rundown: The evolution of SARS-CoV-2 has led to \[…\] The post Concomitant… ## [Cruise ship hantavirus outbreak turns into a global contact tracing test](https://www.2minutemedicine.com/cruise-ship-hantavirus-outbreak-turns-into-a-global-contact-tracing-test/) _2026-06-24 · Deepti Shroff · Infectious Disease | 2 Minute Medicine_ 1. An Andes virus outbreak aboard the MV Hondius expedition cruise ship led to severe respiratory illness, multiple deaths, and contact tracing across 32 countries. 2. The episode is clinically important because Andes virus is the only hantavirus with documented person-to-person transmission, although it does not behave like a highly transmissible airborne pathogen. The Andes \[…\] The post Cruise… ## [Antibiotic prescribing remains high for uncomplicated diverticulitis](https://www.2minutemedicine.com/antibiotic-prescribing-remains-high-for-uncomplicated-diverticulitis/) _2026-06-22 · Adrian Wong · Gastroenterology | 2 Minute Medicine_ 1. In this study, antibiotics were prescribed in nearly all visits for uncomplicated diverticulitis between 2015 and 2025, despite guideline recommendations discouraging routine antibiotic use. 2. Fluoroquinolone-based regimens and amoxicillin-clavulanate were the most commonly prescribed antibiotics, with prescribing patterns shifting toward amoxicillin-clavulanate over time. Evidence Rating… ## [High intake of sugar-sweetened beverages is associated with increased risk of hepatocellular carcinoma](https://www.2minutemedicine.com/high-intake-of-sugar-sweetened-beverages-is-associated-with-increased-risk-of-hepatocellular-carcinoma/) _2026-06-19 · Siwen Liu · Gastroenterology | 2 Minute Medicine_ 1. Increased intake of sugar-sweetened beverages was associated with increased risk of hepatocellular carcinoma and intrahepatic cholangiocarcinoma, while intake of artificially sweetened beverages was not associated with liver cancer risk overall or by subtype. Evidence Rating Level: 2 (Good) Study Rundown: Liver cancer is among the leading causes of cancer mortality worldwide. Consumption of… ## [2MM: AI Roundup: Food and Drug Administration reviews liver injury prediction tool, Joint Commission launches healthcare artificial intelligence certification, governance playbooks aim to standardize adoption, and pediatric hospitals bring generative tools to the frontline](https://www.2minutemedicine.com/2mm-ai-roundup-food-and-drug-administration-reviews-liver-injury-prediction-tool-joint-commission-launches-healthcare-artificial-intelligence-certification-governance-playbooks-aim-to-standardize/) _2026-06-15 · Deepti Shroff · Pediatrics | 2 Minute Medicine_ Food and Drug Administration reviews artificial intelligence tool for liver injury prediction The Food and Drug Administration (FDA) is reviewing an artificial intelligence based drug development tool designed to predict drug induced liver injury, one of the more stubborn safety problems in clinical development. The agency’s Center for Drug Evaluation and Research accepted a letter \[…\] The post… ## [Collect Open Source Legends (Sponsored)](https://crawlproof.com/a/qeey9XVnYct3) _2026-06-15 · **Sponsored**_ Open-licensed art, limited foil trading packs, and optional on-chain mints. ## [Children conceived through infertility treatments may have similar growth compared to naturally conceived children](https://www.2minutemedicine.com/children-conceived-through-infertility-treatments-may-have-similar-growth-compared-to-naturally-conceived-children/) _2026-06-11 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. After accounting for plurality, children conceived through infertility treatments showed similar growth trajectories to those conceived naturally. Evidence Rating Level: 2 (Good) Compared to children conceived naturally, children conceived through medically assisted reproduction (MAR) may experience different birth outcomes and growth patterns. However, evidence on long-term growth trajectories… ## [High-fidelity implementation of enhanced recovery protocols improves outcomes in pediatric gastrointestinal surgery](https://www.2minutemedicine.com/high-fidelity-implementation-of-enhanced-recovery-protocols-improves-outcomes-in-pediatric-gastrointestinal-surgery/) _2026-06-10 · Alexander Uriarte · Gastroenterology | 2 Minute Medicine_ 1. High-fidelity adherence to an enhanced recovery protocol was associated with a significantly shorter length of stay and fewer complications compared to low-fidelity care in pediatric patients undergoing elective gastrointestinal surgery. 2. Protocol adherence improved across study phases, and electronic health record order set integration and favorable site culture were the institutional… ## [A lower volume of polyethylene glycol with ascorbate (MoviPrep) may improve bowel cleansing prior to colonoscopy](https://www.2minutemedicine.com/a-lower-volume-of-polyethylene-glycol-with-ascorbate-may-improve-bowel-cleansing-prior-to-colonoscopy/) _2026-05-26 · Alex Xiang · Gastroenterology | 2 Minute Medicine_ 1. 1 litre polyethylene glycol with ascorbate (1L-PEG-Asc) showed superior bowel cleansing efficacy compared to 2 litre polyethylene glycol with ascorbate (2L-PEG-Asc) in adult patients undergoing colonoscopy for colorectal cancer (CRC) screening. Evidence Rating Level: 1 (Excellent) Colonoscopy is a highly effective procedure for CRC screening and has been shown to reduce CRC mortality.… ## [Adverse pregnancy outcomes is associated with worse offspring cardiovascular health in early adulthood](https://www.2minutemedicine.com/adverse-pregnancy-outcomes-is-associated-with-worse-offspring-cardiovascular-health-in-early-adulthood/) _2026-05-18 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. Exposure to adverse pregnancy outcomes, particularly hypertensive disorders of pregnancy, was associated with worse cardiovascular health and early arterial injury among offspring in early adulthood. Evidence Rating Level: 2 (Good) Study Rundown: Adverse pregnancy outcomes (APOs) have been associated with long-term maternal cardiovascular health (CVH). However, research on the role of APOs in… ## [A non-invasive neurostimulation intervention may improve social communication impairment in children with autism spectrum disorder](https://www.2minutemedicine.com/a-non-invasive-neurostimulation-intervention-may-improve-social-communication-impairment-in-children-with-autism-spectrum-disorder/) _2026-05-05 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. Five days of accelerated continuous theta burst stimulation (a-cTBS) targeting the left primary motor cortex improved social communication impairment in children with autism spectrum disorder. Evidence Rating Level: 1 (Excellent) Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurostimulation technique that has shown efficacy in treating various neuropsychiatric… ## [Perianal lidocaine may improve comfort and efficiency during unsedated adult colonoscopy](https://www.2minutemedicine.com/perianal-lidocaine-may-improve-comfort-and-efficiency-during-unsedated-adult-colonoscopy/) _2026-05-05 · Paary Balakumar · Gastroenterology | 2 Minute Medicine_ 1. Perianal 2% lidocaine gel significantly reduced anal pain and shortened cecal intubation time during unsedated colonoscopy in adults aged 18–40 years. 2. The intervention appeared safe in this small trial and may be especially useful for junior endoscopists, but generalizability is limited by the single-centre design, modest sample size, and exclusion of patients older \[…\] The post Perianal… ## [A robotic approach for ventral hernia repair may improve postoperative outcomes](https://www.2minutemedicine.com/a-robotic-approach-for-ventral-hernia-repair-may-improve-postoperative-outcomes/) _2026-05-04 · Siwen Liu · Gastroenterology | 2 Minute Medicine_ 1. Robotic component separation for ventral hernia repair was associated with lower postoperative complication rates, shorter length of stay, and fewer readmissions compared to the open approach. Evidence Rating Level: 2 (Good) Surgical repair of complex ventral hernias is challenging and associated with high morbidity. While component separation is commonly used to repair complex ventral \[…\] The… ## [Early child-rearing conditions may improve psychosocial outcomes in adopted children compared to unadopted biological siblings](https://www.2minutemedicine.com/early-child-rearing-conditions-may-improve-psychosocial-outcomes-in-adopted-children-compared-to-unadopted-biological-siblings/) _2026-04-27 · Siwen Liu · Pediatrics | 2 Minute Medicine_ 1. Adopted individuals who experienced improved environmental conditions had better long-term psychosocial outcomes than their unadopted biological siblings, with some advantages also observed in the next generation. Evidence Rating Level: 2 (Good) Improving home environments during early life can benefit later cognitive, educational, and behavioural outcomes. However, the long-term protective…