PAINS and Prejudice

<< previous || next >> PAINS ( p an a ssay in terference compound s ) filters have exerted a hold over the drug discovery community ever since the BH2010 study appeared over 15 years ago. Initially I didn’t take much notice of PAINS filters and, in any case, I’d already moved on from analysis of high-throughput screening (HTS) output by that point (I might add ‘thankfully’ because looking at too…