Dietary changes and pharmacologic interventions may prevent recurrent nephrolithiasis

1. In this systematic review, low-strength evidence suggests that increased fluid intake, dietary modification (normal-to-high calcium, low protein, low sodium), and pharmacologic therapies (thiazides, alkali therapy, allopurinol, and acetohydroxamic acid) may reduce kidney stone recurrence in adults. 2. The overall strength of evidence is limited, as most included studies had moderate-to-high…