Thyroid Hormone as the Guardian of Form

The Thermodynamic Imperative Orthodox endocrinology frames thyroid regulation through the lens of the Hypothalamic-Pituitary-Thyroid axis—a homeostatic feedback loop where TSH serves as the master regulator, keeping circulating T4 and T3 within statistical reference ranges. This model has clinical utility. It generates treatment protocols. But it increasingly fails to account for observations that…