MYC: The Master Driver of Cancer Growth

Among the thousands of genes implicated in cancer, few have had as profound an impact as MYC. Unlike many oncogenes that drive a limited number of tumors, MYC acts as a universal amplifier of malignant behavior. It regulates cellular proliferation, metabolism, protein synthesis, mitochondrial function, stemness, angiogenesis, immune evasion, and genomic instability. Estimates suggest that…