AI Simulations Reveal Treatment Synergies Clinical Trials Will Never Test (2026)

Executive Brief Modern oncology is constrained by a paradox: Clinical trials are the gold standard. Yet they are structurally incapable of testing most biologically plausible treatment combinations. Metabolic therapies, repurposed drugs, dietary interventions, and immune-modulating strategies form a combinatorial space too large, too unprofitable, and too complex for conventional trial frameworks.…