Fever With Dexmedetomidine

Dexmedetomidine (Precedex) is a selective alpha-2 agonist I frequently use as a cardiac anesthesiologist and intensivist to provide analgosedation before extubation. Beyond its sedative and sympatholytic effects, dexmedetomidine has been increasingly implicated in drug-induced fever. Although listed in the FDA label, recent literature provides a clearer picture. A post hoc analysis of 703…