198,494 Patient Encounters Across 9 Hospitals Just Delivered the Fairest Test Yet of the Epic Sepsis Model Version 2. Predictive Performance Depends on Which Sepsis Definition You Apply, and False....

The April 2026 JAMA Network Open study from Massachusetts General Brigham, senior-authored by Chanu Rhee, evaluated the widely deployed Epic Sepsis Model version 2 across three standard sepsis definitions (Sepsis-3, SEP-1, and CDC Adult Sepsis Event).