Therapeutic Effect of Myostatin/Activin Blockage and Dietary Restriction in Modulation of Platelet Activation Markers of Progeroid Mouse Model

Aging-related decline in hematopoietic and platelet function is a hallmark of DNA repair deficiency syndromes, yet the impact of metabolic and pharmacological interventions on platelet biology in this context remains unclear. This study addresses this gap by investigating whether dietary restriction (DR) and myostatin/activin blockade through soluble Activin Receptor Type IIB (sActRIIB) can…