IN VIVO BIOCOMPATIBILITY EVALUATION OF NORFLOXACIN-LOADED CHITOSAN NANOFIBERS AND BORONIC ALDEHYDE-FUNCTIONALIZED DERIVATIVES IN RAT

Chitosan-based nanofibers can serve as carriers for antimicrobial agents, providing controlled drug release and biocompatibility, which are crucial for tissue integration and healing. This study aimed to evaluate the in vivo biocompatibility of norfloxacin-loaded chitosan nanofibers (NorC) and norfloxacin-loaded chitosan nanofibers functionalized with boronic aldehyde (NorCB), in comparison with…