# aged (blogs) — RSS Amplifier Recent posts from the 6 feeds in the RSS Amplifier directory that cover aged. Page: Feed: --- ## [2039 Days](https://howlonghastrumpbeeninoffice.com/2039/) _2026-08-21 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2039 days ## [Health system in crisis because of National’s choices – Labour](https://thedailyblog.co.nz/health-system-in-crisis-because-of-nationals-choices-labour/) _2026-08-21 · The Daily Blog · Raw News – The Daily Blog_ National has spent the last two years pretending they’ve hired thousands of new nurses but yesterday, they admitted the real... ## [National bungles Winter Energy Payments – Labour](https://thedailyblog.co.nz/national-bungles-winter-energy-payments-labour/) _2026-08-21 · The Daily Blog · Raw News – The Daily Blog_ Christopher Luxon should apologise to the 15,000 New Zealanders whose Winter Energy Payment stopped because of changes National rushed under... ## [TIMP2 Protein Therapy Favorable Adjusts the Behavior of Microglia in the Aging Brain](https://www.fightaging.org/archives/2026/08/timp2-protein-therapy-favorable-adjusts-the-behavior-of-microglia-in-the-aging-brain/) _2026-08-21 · Reason · Fight Aging!_ The central nervous system is relatively isolated from the rest of the body; the blood-brain barrier ensures that only certain cells and molecules are permitted to pass between the body and brain. Many cell populations are specific to the brain, and even the immune systems in brain and body are relatively isolated and different from one another. Microglia are innate immune cells of the central… ## [The NLRP3 Inflammasome in Age-Related Macular Degeneration](https://www.fightaging.org/archives/2026/08/the-nlrp3-inflammasome-in-age-related-macular-degeneration/) _2026-08-21 · Reason · Fight Aging!_ The retina is a part of the central nervous system, and as such is subject to a variety of forms of age-related neurodegeneration, culminating in conditions such as macular degeneration. The chronic inflammation characteristic of old age is just as important to neurodegeneration in the retina just as it is in the brain. Inflammatory signaling, necessary and useful in the short term, becomes… ## [A Histological Aging Clock](https://www.fightaging.org/archives/2026/08/a-histological-aging-clock/) _2026-08-21 · Reason · Fight Aging!_ Histological studies investigate the fine structure of tissues, usually thinly sliced and mounted on slides, stained in ways that emphasis specific features, and imaged via a microscope. Here, researchers demonstrate that the characteristic age-related changes in the cell and tissue features present in histological images can form the basis for development of aging clocks for research use. Any… ## [2038 Days](https://howlonghastrumpbeeninoffice.com/2038/) _2026-08-20 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2038 days ## [RANKL Inhibition Slows Aging in Progeroid Mice](https://www.fightaging.org/archives/2026/08/rankl-inhibition-slows-aging-in-progeroid-mice/) _2026-08-20 · Reason · Fight Aging!_ RANKL is best studied in the context of bone remodeling. Its activity, binding to the cell surface receptor RANK, is necessary for the function of the osteoclast cells that break down bone extracellular matrix. Bone tissue is in a constant state of remodeling, built up by osteoblast cells and broken down by osteoclast cells. The loss of bone mineral density that leads to osteoporosis arises from a… ## [Age-Related Changes in Metabolism that Contribute to Inflammatory Microglia in the Brain](https://www.fightaging.org/archives/2026/08/age-related-changes-in-metabolism-that-contribute-to-inflammatory-microglia-in-the-brain/) _2026-08-20 · Reason · Fight Aging!_ In recent years, an increasing level of attention has been given to microglia as an important contribution to neurodegeneration in the aging brain. Microglia are innate immune cells resident in the central nervous system, analogous to the macrophages found elsewhere in the body. They are deeply involved in the complex processes of normal tissue function and maintenance, not just a defense against… ## [A Review of the Present State of Data for Metformin as a Geroprotective Drug](https://www.fightaging.org/archives/2026/08/a-review-of-the-present-state-of-data-for-metformin-as-a-geroprotective-drug/) _2026-08-20 · Reason · Fight Aging!_ Researchers here review the present state of research and use of metformin as a geroprotective drug, intended to modestly slow aging. They are largely on point, if somewhat too accepting of the quality of the existing human data. While effective as a treatment for metabolic syndrome and type 2 diabetes, metformin is nowhere near as good a choice as rapamycin if forced to pick a geroprotective drug… ## [Make any domain metal (Sponsored)](https://crawlproof.com/a/suzCQI9XAUoJ) _2026-08-20 · **Sponsored**_ Turn any domain into a blacked-out metal landing page with an email waitlist ## [2037 Days](https://howlonghastrumpbeeninoffice.com/2037/) _2026-08-19 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2037 days ## [Mechanisms by Which Air Pollution Contributes to Parkinson's Disease](https://www.fightaging.org/archives/2026/08/mechanisms-by-which-air-pollution-contributes-to-parkinsons-disease/) _2026-08-19 · Reason · Fight Aging!_ Most forms of air pollution (with a particular focus on fine particles) are now well established to contribute to age-related conditions at the level of exposure that is experienced in much of the industrialized world. Typically matters are worse in less wealthy regions, particularly those using solid fuel for domestic cooking and heating. Nonetheless, there is enough of a contribution even in… ## [Greater Vascular Health in Mid-Life Reduces Later Risk of Dementia](https://www.fightaging.org/archives/2026/08/greater-vascular-health-in-mid-life-reduces-later-risk-of-dementia/) _2026-08-19 · Reason · Fight Aging!_ The state of the cardiovascular system has a strong impact on the aging of the brain. The brain requires an sizable supply of energy, delivered via the bloodflow, and suffers when that supply is reduced. With age, the vascular system loses smaller vessels, while larger vessels become damaged. Loss of physical fitness also reduces blood supply. Additionally, damaged blood vessels allow leakage of… ## [XPRIZE Healthspan Finalist Teams Announced](https://www.fightaging.org/archives/2026/08/xprize-healthspan-finalist-teams-announced/) _2026-08-19 · Reason · Fight Aging!_ From one perspective, the XPRIZE Healthspan research prize is a way to encourage what should be happening to a far greater extent in the development of means to treat aging as a medical condition, which is to assess which approaches are better than others. The field spends too much time on approaches that cannot improve on lifestyle choices, for example. Ideally this competitive assessment… ## [2036 Days](https://howlonghastrumpbeeninoffice.com/2036/) _2026-08-18 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2036 days ## [Reviewing the Aging of the Gut Microbiome and Interventions Known to Improve Its Composition](https://www.fightaging.org/archives/2026/08/reviewing-the-aging-of-the-gut-microbiome-and-interventions-known-to-improve-its-composition/) _2026-08-18 · Reason · Fight Aging!_ The composition of the gut microbiome is influential on long term health and the progression of aging. Unfortunately, this composition changes with age for a range of reasons yet to be fully explored, but which include the decline of the immune system and growing leakage of the intestinal barrier. With age, populations of inflammatory microbial species grow at the expense of microbial species that… ## [In Search of Robust Biomarkers to Connect Cellular Senescence to Age-Related Chronic Inflammation](https://www.fightaging.org/archives/2026/08/in-search-of-robust-biomarkers-to-connect-cellular-senescence-to-age-related-chronic-inflammation/) _2026-08-18 · Reason · Fight Aging!_ Senescent cells accumulate with age, and actively secrete pro-inflammatory signals. The present understanding of senescent cell biochemistry and animal studies of senescent cell clearance strongly suggest that senescent cells in aged tissues provide a major contribution to the characteristic chronic inflammation of old age, disruptive to tissue structure and function. As researchers here note,… ## [Quantifying the Reduction in Mortality Risk that Accompanies Physical Fitness](https://www.fightaging.org/archives/2026/08/quantifying-the-reduction-in-mortality-risk-that-accompanies-physical-fitness/) _2026-08-18 · Reason · Fight Aging!_ It is well established that physical fitness (and the level of activity and other lifestyle choices required to sustain it) correlate with a lower risk of mortality and longer life expectancy. Human data largely cannot provide evidence for causation, but that greater activity and fitness slow aging and extend life is robustly demonstrated in animal studies. Many large epidemiological studies have… ## [2035 Days](https://howlonghastrumpbeeninoffice.com/2035/) _2026-08-17 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2035 days ## [Reprogramming of Corticospinal Neurons Improves Recovery of Function in Mice Following Stroke](https://www.fightaging.org/archives/2026/08/reprogramming-of-corticospinal-neurons-improves-recovery-of-function-in-mice-following-stroke/) _2026-08-17 · Reason · Fight Aging!_ Rehabilitation following a stroke that causes significant loss of function is a slow, painful, and uncertain process. The concept underlying these efforts is that the brain will attempt to rebuild neural connections given sufficient efforts to use lost and diminished function. This does happen to some degree, but far less so in aged patients. Changes in brain circuitry require neuroplasticity: the… ## [Pirate.io on Google Play (Sponsored)](https://crawlproof.com/a/4s3VPLH4t8ZH) _2026-08-17 · **Sponsored**_ Open the Pirate.io listing on Google Play to view the app’s details. ## [Aged Care Report Step In Right Direction, But Reform Must Fix Pay Equity For Care Workers – PSA](https://thedailyblog.co.nz/aged-care-report-step-in-right-direction-but-reform-must-fix-pay-equity-for-care-workers-psa/) _2026-08-17 · The Daily Blog · Raw News – The Daily Blog_ Today’s Ministerial Advisory Group report on aged care will only deliver the system older New Zealanders need if it comes... ## [Long-Term Investment In Aged Care Can’t Wait – Delaying It Will Only Increase The Cost – Green](https://thedailyblog.co.nz/long-term-investment-in-aged-care-cant-wait-delaying-it-will-only-increase-the-cost-green/) _2026-08-17 · The Daily Blog · Raw News – The Daily Blog_ The Green Party welcomes the release of “A place to grow old: Securing the future of aged care” report and... ## [The Aged Immune System Fails to Clear Senescent Cells](https://www.fightaging.org/archives/2026/08/the-aged-immune-system-fails-to-clear-senescent-cells/) _2026-08-17 · Reason · Fight Aging!_ Cells become senescent constantly throughout life, in response to damage, stress, or reaching the Hayflick limit on replication. A senescent cell ceases to replicate, grows in size, and begins to secrete a potent mix of pro-inflammatory signals. In youth, the immune system efficiently clears senescent cells. Clearance falters in later life, however, and this failure of the immune system to keep up… ## [The State of Stem Cell Therapies](https://www.fightaging.org/archives/2026/08/the-state-of-stem-cell-therapies/) _2026-08-17 · Reason · Fight Aging!_ First generation stem cell therapies that use a variety of cell sources and protocols are widely used in the medical tourism industry. A more limited set of such therapies are used in more regulated medical systems. The aspirational goal in the field of stem cell medicine is to induce regeneration of aged and damaged tissues to improve function, but this outcome remains unreliable. Stem cell… ## [2034 Days](https://howlonghastrumpbeeninoffice.com/2034/) _2026-08-16 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2034 days ## [Security Council: Escalating Attacks Threaten Peace In Yemen – UN News](https://thedailyblog.co.nz/security-council-escalating-attacks-threaten-peace-in-yemen-un-news/) _2026-08-16 · The Daily Blog · Raw News – The Daily Blog_ What you need to know The Houthis took de facto control of Yemen’s capital, Sana’a, in 2014, with the UN... ## [ACT Wants Public Service To Be A Bad Employer, Exposing The Real Agenda Behind Its ‘Reset’ – PSA](https://thedailyblog.co.nz/act-wants-public-service-to-be-a-bad-employer-exposing-the-real-agenda-behind-its-reset-psa/) _2026-08-16 · The Daily Blog · Raw News – The Daily Blog_ ACT coming after requirements for the public service to be a good employer says everything about the party’s real agenda,... ## [Fight Aging! Newsletter, August 17th 2026](https://www.fightaging.org/archives/2026/08/fight-aging-newsletter-august-17th-2026/) _2026-08-16 · Reason · Fight Aging!_ Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter, please visit: https://www.fightaging.org/newsletter/. To unsubscribe, send email or reply to this email at… ## [Afghanistan: One In 10 Children Acutely Malnourished As Plummeting Funding Closes Nearly 600 Health Facilities – Save the Children](https://thedailyblog.co.nz/afghanistan-one-in-10-children-acutely-malnourished-as-plummeting-funding-closes-nearly-600-health-facilities-save-the-children/) _2026-08-15 · The Daily Blog · Raw News – The Daily Blog_ The number of acutely malnourished children in Afghanistan is increasing with nearly one in 10 children under five suffering from... ## [Thousands Of NZers Demand ‘Hands Off Conservation Land’ In Nationwide Day Of Action – Greenpeace](https://thedailyblog.co.nz/thousands-of-nzers-demand-hands-off-conservation-land-in-nationwide-day-of-action-greenpeace/) _2026-08-15 · The Daily Blog · Raw News – The Daily Blog_ Thousands of people across Aotearoa have taken part in a nationwide day of action today, calling on the Coalition Government... ## [Auto-trade Cross-Exchange Gaps (Sponsored)](https://crawlproof.com/a/PKUhh5gKTWwB) _2026-08-15 · **Sponsored**_ Find cross-exchange spreads, backtest strategies, and execute automatically with risk controls. ## [2033 Days](https://howlonghastrumpbeeninoffice.com/2033/) _2026-08-15 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2033 days ## [New Russia Sanctions Expose Double Standard Towards Israel – Palestine Solidarity Network Aotearoa](https://thedailyblog.co.nz/new-russia-sanctions-expose-double-standard-towards-israel-palestine-solidarity-network-aotearoa/) _2026-08-14 · The Daily Blog · Raw News – The Daily Blog_ PSNA is urging the government to ‘even-up’ its foreign policy going into the November election. PSNA is responding to Foreign... ## [National need to end LNG obsession – Labour](https://thedailyblog.co.nz/national-need-to-end-lng-obsession-labour/) _2026-08-14 · The Daily Blog · Raw News – The Daily Blog_ The Government should not sign off its proposed LNG import terminal before New Zealanders have their say at the election.... ## [National remembers the South Island exists – Labour](https://thedailyblog.co.nz/national-remembers-the-south-island-exists-labour/) _2026-08-14 · The Daily Blog · Raw News – The Daily Blog_ National has spent nearly three years neglecting the South Island. Now with an election looming, it’s frantically dusting off some... ## [Why Do Myesthenia Gravis Patients Live Five Years Longer than the General Population?](https://www.fightaging.org/archives/2026/08/why-do-myesthenia-gravis-patients-live-five-years-longer-than-the-general-population/) _2026-08-14 · Reason · Fight Aging!_ Myesthenia gravis is a rare autoimmune condition in which a specific receptor needed for nerve impulses to pass through the neuromuscular junction to active muscle fibers is blocked or destroyed by immune activity. This leads to muscle weakness that varies over time, and can progress to be life-threatening in a minority of cases. The prognosis is good for the majority of patients, however. While… ## [2032 Days](https://howlonghastrumpbeeninoffice.com/2032/) _2026-08-14 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2032 days ## [How Tauopathy Promotes Mitochondrial Dysfunction, and Prospects for Sabotaging that Mechanism](https://www.fightaging.org/archives/2026/08/how-tauopathy-promotes-mitochondrial-dysfunction-and-prospects-for-sabotaging-that-mechanism/) _2026-08-14 · Reason · Fight Aging!_ Tauopathies emerge in the aging brain, a pathological level of phosphorylation of the tau protein that is disruptive to cell function. Evidence suggests a feedback loop between tau phosphorylation and consequent aggregation into neurofibrillary tangles on the one hand and chronic inflammation in brain tissue on the other, ultimately leading to the widespread death of neurons. Here, researchers… ## [Mechanisms of Neuroprotection Arising from Exercise](https://www.fightaging.org/archives/2026/08/mechanisms-of-neuroprotection-arising-from-exercise/) _2026-08-14 · Reason · Fight Aging!_ Muscle tissue is metabolically active. In response to use during physical activity, muscle cells secrete a range of signals, as a class now called myokines or exerkines. These signals produce overall beneficial effects on cell behavior and tissue function throughout the body. The precise details of this process are still under investigation, and only the major signals are fairly well mapped - a… ## [2031 Days](https://howlonghastrumpbeeninoffice.com/2031/) _2026-08-13 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2031 days ## [Is it Reasonable to Say that Obesity Accelerates Aging?](https://www.fightaging.org/archives/2026/08/is-it-reasonable-to-say-that-obesity-accelerates-aging/) _2026-08-13 · Reason · Fight Aging!_ In order to produce an airtight answer to the question of whether obesity accelerates aging, versus merely being very bad for one's health, one has to have an airtight definition of aging. It is always possible to fall back to the oldest and least useful definition of aging, which is a rise in risk of mortality over time driven by intrinsic causes. Arguably the effects of obesity fit that… ## [Stop Data Centres NZ Mobilises As Hyperscale Plans Spread – New Taranaki Group Forms – Stop Data Centres NZ](https://thedailyblog.co.nz/stop-data-centres-nz-mobilises-as-hyperscale-plans-spread-new-taranaki-group-forms-stop-data-centres-nz/) _2026-08-13 · The Daily Blog · Raw News – The Daily Blog_ Communities across New Zealand are organising against the rapid expansion of hyperscale data centres, with a protest taking place and... ## [Targeting Senescent Cells to Treat Age-Related Chronic Pulmonary Disease](https://www.fightaging.org/archives/2026/08/targeting-senescent-cells-to-treat-age-related-chronic-pulmonary-disease/) _2026-08-13 · Reason · Fight Aging!_ A sizable body of evidence points to a meaningful role for the accumulation of senescent cells in the onset and development of age-related pulmonary conditions such as idiopathic pulmonary fibrosis. These are conditions characterized by chronic inflammation and harmful structural remodeling in lung tissue. Animal studies suggest that senolytic therapies to clear senescent cells can turn back the… ## [Reviewing the State of Aging Clocks for the Brain](https://www.fightaging.org/archives/2026/08/reviewing-the-state-of-aging-clocks-for-the-brain/) _2026-08-13 · Reason · Fight Aging!_ There are now scores of aging clocks in the literature, most of which have come and gone and see little adoption. Most research is focused on gathering more data for handful of mainstream clocks, but these clocks are intended to capture a measure of aging generally across the whole body, keyed to outcomes such as mortality risk. Evidence suggests that different organs and tissues can age at… ## [2030 Days](https://howlonghastrumpbeeninoffice.com/2030/) _2026-08-12 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2030 days ## [Summarizing the State of Hyperfunction Theories of Aging](https://www.fightaging.org/archives/2026/08/summarizing-the-state-of-hyperfunction-theories-of-aging/) _2026-08-12 · Reason · Fight Aging!_ The major divide in theories of aging lies between the mainstream camp of damage accumulation and antagonistic pleiotropy on the one hand, and the minority camp of programmed aging theories on the other. The damage accumulation camp sees aging as a side-effect of the focus of evolutionary mechanisms on early life reproductive success, favoring the development of biological systems that are… ## [Iron Metabolism and Ferroptosis in Atherosclerosis](https://www.fightaging.org/archives/2026/08/iron-metabolism-and-ferroptosis-in-atherosclerosis/) _2026-08-12 · Reason · Fight Aging!_ Iron metabolism is strongly connected to oxidative stress, the excessive production of reactive oxygen species and other oxidative molecules that outpaces the ability of cells to avoid, resist, or repair the consequent damage. It can lead to a form of programmed cell death called ferroptosis. Here, researchers describe how iron metabolism and ferroptosis are seen to contribute to the development… ## [Towards Reliability and Accuracy in the Measurement of Biological Age](https://www.fightaging.org/archives/2026/08/towards-reliability-and-accuracy-in-the-measurement-of-biological-age/) _2026-08-12 · Reason · Fight Aging!_ That we cannot accurately and robustly measure biological age is a major impediment to the development of rejuvenation therapies. Without the ability to quickly focus on approaches with the largest effects on biological age, the field spends far too much time on marginal classes of therapy, and optimization of any given approach is challenging, haphazard, and slow. The development of aging clocks… ## [2029 Days](https://howlonghastrumpbeeninoffice.com/2029/) _2026-08-11 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2029 days ## [Trial Results for a PD-L1 Antibody Therapy to Reduce Inflammation in Alzheimer's Disease](https://www.fightaging.org/archives/2026/08/trial-results-for-a-pd-l1-antibody-therapy-to-reduce-inflammation-in-alzheimers-disease/) _2026-08-11 · Reason · Fight Aging!_ Alzheimer's disease, and the other common age-related neurodegenerative conditions, are characterized by chronic inflammation in brain tissue. Aging in general is characterized by an increased level of constant inflammatory signaling. Numerous different mechanisms contribute to this constant inflammation, such as maladaptive reactions to mitochondrial DNA fragments released into the cytoplasm as a… ## [2028 Days](https://howlonghastrumpbeeninoffice.com/2028/) _2026-08-10 · howlonghastrumpbeeninoffice · How Long Has Trump Been In Office?_ Some middle aged white dude with hair that has been growing for 2028 days