Reprogramming of Corticospinal Neurons Improves Recovery of Function in Mice Following Stroke

Rehabilitation following a stroke that causes significant loss of function is a slow, painful, and uncertain process. The concept underlying these efforts is that the brain will attempt to rebuild neural connections given sufficient efforts to use lost and diminished function. This does happen to some degree, but far less so in aged patients. Changes in brain circuitry require neuroplasticity: the…