The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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Martin Casado joins MTS hosts Theo Jaffee and Sophia Dew to unpack where value is actually accruing in AI, why this technology cycle looks fundamentally different from previous waves, and whether the frontier labs will ultimately capture most of the market. Martin explains why AI has turned venture into a scale-up capital game, where small teams can productively deploy extraordinary amounts of…
a16z's Joel De La Garza is joined by Aaron Zollman, Deputy CISO at Microsoft Gaming, to discuss how security teams can embrace AI agents without losing control. Aaron shares Microsoft's experience with OpenClaw, from the initial instinct to ban it to figuring out how to make it safe to use. They unpack what agents mean for identity, permissions, containerization, and monitoring, as well as how AI…
Elena Burger is joined by a16z’s Angela Strange and Gabriel Vasquez to discuss the rise of the "borderless founder": entrepreneurs who bring the networks and insights of their home markets together with the talent, capital, and speed of Silicon Valley to build global companies. Angela and Gabriel trace how a16z's international investing efforts grew from early work in Latin America into a broader…
a16z General Partner David George is joined by Grant LaFontaine, co-founder of Whatnot, to unpack how a marketplace that started with collectibles evolved into one of the world's leading live shopping platforms. Grant traces the company's origins from selling Pokémon cards online as a kid to discovering live commerce by watching Whatnot's earliest customers hack together sales on social media.…
a16z's Joel De La Garza is joined by Nick Warner of Neo and Max Pollard of Cotool to discuss what happens when cybersecurity tools built to defend against humans and malware suddenly have to contend with AI agents. As frontier models become more capable of finding and exploiting vulnerabilities, many of the assumptions underlying traditional security are beginning to break. They explore why…
a16z General Partner David George is joined by Will Gaybrick, President of Product & Business at Stripe, to discuss how AI is changing the way Stripe builds products, organizes teams, and thinks about the future of internet commerce. Stripe has evolved from a payments company into a multi-product financial infrastructure platform, while a new generation of AI companies is growing and monetizing…
Ben Horowitz, Travis Kalanick, and Erik Torenberg take the stage at Atoms' launch event for a candid fireside conversation about entrepreneurship, company building, and why Kalanick believes the next industrial revolution will be powered by AI. They revisit pivotal moments from Uber's history, including the decision not to acquire Lyft, lessons from scaling one of the world's fastest-growing…
Elena Burger is joined by a16z's Andy McCall and Joe Schmidt to break down two very different ways AI startups can go to market: the lighthouse and the landgrab. Should founders win a handful of marquee customers whose credibility unlocks an entire industry, or move quickly across a broad market where the ROI already speaks for itself? Drawing on Joe's Lighthouse or Landgrab framework and Andy's…
Anish Acharya is joined by Garry Tan, President and CEO of Y Combinator, for a conversation about how AI is rewriting the startup playbook, why founders should be more ambitious than ever, and what two decades of Silicon Valley booms, busts, and missed opportunities have taught Garry about building what's next. Garry reflects on turning down an early opportunity to join Palantir, why chasing…
a16z's Joel De La Garza is joined by Emilio Escobar, Chief Information Security Officer at Datadog, to discuss what it takes to secure a company where nearly every employee is using AI and more than 4,000 engineers are working with coding agents. Rather than trying to block new tools, Emilio explains why Datadog chose to embrace AI early and build the security infrastructure needed to use it…
