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TGen Talks

TGen Talks explores the human genome to tackle the latest science and discoveries in cancer, neurological disorders, rare diseases, metabolic disorders and infectious disease. Learn about causes and potential cures in our monthly podcast!

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Episode 93: Dr. John Fryer Discusses Mentorship in Biomedical Research

In this episode of TGen Talks, we explore the art and responsibility of mentorship in biomedical research. Behind every breakthrough is not just data and experiments, but the guidance of seasoned scientists who shape the next generation. And while the results may not appear in a lab notebook, they’re just as important. TGen neuroscientist and educator, Dr. John Fryer, joins the podcast to share…

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Episode 92: Helios Scholar Saahithi Mallapragada

For many Arizona students, the path into science begins with a single summer that reshapes their confidence and their future. Since 2007, the Helios Scholars Program at TGen has been that turning point. Each year, Helios Scholars spend eight weeks working directly with TGen researchers exploring cancer biology, neurological and infectious disease, diabetes, and the fast‑growing world of…

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Episode 91: Drs. Simona Migliozzi and Luciano Garofano

May is Brain Tumor Awareness Month. In this episode, meet two new TGen researchers whose shared love of science—and math—first brought them together in the lab and later in life. Drs. Simona Migliozzi and Luciano Garofano are married to each other and to their work. They discuss their education in Italy, their research journeys across institutions in the U.S., and the path that ultimately led them…

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Episode 90: Study Links Obesity and Cancer

It’s well known that smoking is the number one factor that significantly increases your risk of developing cancer over a lifetime. But obesity also poses an increased risk. While the relationship is well known, the reasons behind the link between body weight and cancer were not … until now. In this episode of TGen Talks, Dr. Cristian Tomasetti, senior author on a recent study in Cancer Research,…

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Episode 89 Dr. Jonathan Keats

March is Multiple Myeloma Awareness Month. In this episode, we speak with TGen Associate Professor Jonathan Keats, Ph.D. Dr. Keats’ revisits the COMPASS study from the Multiple Myeloma Research Foundationm a 12-year research project that examined the different forms of this blood cancer and revealed why some patients respond well to treatment while others face more aggressive disease. His work on…

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Episdoe 88: Closing in on One Million

Why do some people stay mentally sharp well into their seventies and eighties, while others begin to struggle with memory much earlier in life? MindCrowd, an ambitious online brain study created at TGen, set out to explore that question more than a decade ago. Instead of bringing small groups of volunteers into a lab, Matt Huentelman, Ph.D., and his team did something almost unheard of at the…

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Episode 87: From Deadly to Detectable?

Episode 87 of TGen Talks features Dr. Haiyong Han, who dives into his latest work on one of the deadliest of cancers: pancreatic cancer. He breaks down why this disease is so hard to catch early, how it can grow silently for years before symptoms appear, and why identifying true positives in the general population is such a big challenge. Dr. Han also shares promising progress toward a new…

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Liquid Biopsy TGT September

In this episode of TGen Talks, we sit down with three researchers who are working to make cancer care safer and more precise for some of the most vulnerable patients—children with rare brain tumors. Dr. Floris Barthel, Dr. Shea Gallus, and graduate student Sharvari Mankame are part of a team at TGen and Phoenix Children’s Hospital exploring liquid biopsies—a method that uses small samples of blood…

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Episode 85: Runway for Research

What connects a fashion show to biomedical research? More than you'd expect—especially in the fight against women’s cancers and the local support for TGen and City of Hope. TGen’s 5th annual Runway for Research takes place on Friday, October 17, in partnership with Neiman Marcus, Scottsdale Fashion Square, and City of Hope Phoenix. Runway for Research blends fashion and purpose, supporting…

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Episode 84 Precision Medicine

What if medicine worked to get you healthier overall—not just people like you or for one or another symptom? In the latest episode of TGen Talks, host Karie Dozer sits down with Nicholas Schork, Ph.D., and Laura Goetz, M.D., co-authors of a recent commentary published in Nature Communications, From Precision Interventions to Precision Health, to explore the promise—and complexity—of truly…

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