Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.
Mental health remains one of medicine's greatest unmet needs. In this episode, Jacob Hooker explains how Sensorium Therapeutics is searching for new psychiatric medicines by combining traditional plant knowledge with cutting-edge drug development. Jacob joins Rafael Rosengarten to discuss how centuries of ethnobotanical knowledge, modern AI, and medicinal chemistry are helping uncover new…
In episode 58, Rafael sits down with James Zanewicz , CEO of Connect, to discuss the art and science of building innovation ecosystems. From Connect's origins as the world's first accelerator to the future of AI-powered healthcare, James shares lessons from a career spanning science, law, technology transfer, academic medicine, and ecosystem development. Together, they explore what makes San Diego…
In this episode, Rafael Rosengarten sits down with Lisa Gurry , Chief Business Officer at GeneDx, to discuss the transformative role of genomic testing in rare disease diagnosis, therapeutic discovery, and precision medicine. Lisa shares GeneDx's mission to shorten the diagnostic odyssey for patients and families, explains how genomic data is accelerating drug development, and reflects on her…
In this episode, Rafael Rosengarten sits down with Dr. Kamal Jethwani , VP of Digital Ventures at Moffitt Cancer Center, CEO of AccelerOnc Studio, and consulting CEO of Decimal Health. With over two decades in digital health, Kamal shares how Moffitt is transforming cutting-edge oncology expertise into scalable AI-native companies, why operational implementation matters more than most founders…
Precision oncology promises more data, more insight, and better decisions, yet in practice it often brings more complexity. In a new episode Rafael Rosengarten is joined by Dr. Shakti Ramkissoon , VP of Oncology at Labcorp, to unpack the realities on the ground. From access gaps, reimbursement challenges and fragmented workflows to the promise of longitudinal data and AI-enabled clarity, Dr.…
In this episode, Rafael Rosengarten speaks with Dr. Sean Khozin , CEO of the CEO Roundtable on Cancer. Sean shares how pre-competitive collaboration across industry, academia, and regulators is helping address some of the biggest challenges in oncology. The conversation explores the role of data sharing initiatives like Project Data Sphere, the promise of AI in clinical trials and discovery, and…
In this episode, I’m joined by Colette Delawalla , founder and CEO of Stand Up For Science. What began as frustration over a federal “banned words” list evolved into a national mobilization effort to defend scientific freedom and evidence-based policymaking. We talk about the organization’s origin story, its National Day of Action on March 7, 2026, the communication gap in science on the political…
In this episode, I’m joined by my longtime friend Ian Simon , Head of Biotechnology at Aspis Intelligence. Ian’s path runs from grad school vaccine research at Yale to senior roles at the White House, HHS, NIH, the State Department, and the Office of Long Covid. We talk about de-risking young biotech companies, what Covid taught us about science and public health, and how new technologies like AI…
In this episode Rafael sits down with Michelle Chen , President and CEO of Form Bio, a techbio company using AI to advance genome engineering and the development of genetic medicines. Michelle shares her zigzag journey from scientist to executive, how her team is tackling the biggest bottlenecks in gene therapy, and why AI has become essential in designing safer, more effective treatments. TPM…
Today I’m joined by Mike Rossi , Vice President of Translational Science and Multi-modal Real-World Evidence Solutions at ConcertAI. Mike has built a career at the intersection of genomics, data science, and oncology, helping to bridge the gap between research and real-world clinical practice. We talk about what real-world data really means, how it becomes actionable evidence, and what it takes to…
