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Talking Biotech with Dr. Kevin Folta

Talking Biotech is a weekly podcast that uncovers the stories, ideas and research of people at the frontier of biology and engineering. Each episode explores how science and technology will transform agriculture, protect the environment, and feed 10 billion people by 2050. Interviews are led by Dr. Kevin Folta, a professor of molecular biology and genomics.

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Meat Proteins in Plants

In this episode, Dr. Alexia Groff discusses her groundbreaking research on expressing mammalian myoglobin in plants using chloroplast transformation. We explore the implications for food production, biosecurity, and future applications in meat substitutes and nutritional enhancement. Chloroplast inheritance reduces gene flow risk, enhancing biosafety. Heterologous expression in plants can produce…

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New Strategies in Early ALS Detection

This episode explores the cutting-edge advancements in ALS diagnostics and treatment, highlighting how AI and digital health are transforming patient care and research. Guest Indo Navar shares her journey from Silicon Valley entrepreneurship to pioneering innovative solutions for ALS and other neurodegenerative diseases.

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A new strategy in the war on obesity

In this episode, Kevin Folta interviews Dr. Erik Ingelsson about innovative RNA-based therapies for obesity, focusing on the potential of silencing RNA and gene editing to target visceral fat and improve metabolic health.

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Cameron English-The Debate on Conventional vs Organic Farming

The debate continues on organic vs conventional farming. Cameron and Kevin give their views on this growing subject!

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Stop Political Interference in Federal Science Grants! With Dr. Colette Delawalla

In this episode, Kevin Folta interviews Dr. Colette Delawalla about the threats to scientific integrity posed by recent political and administrative changes. They discuss the importance of federal funding, the impact of proposed policies, and how the scientific community can respond to defend science and democracy. You Can Help Change the Federal Government views!!

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The Future of Agriculture -- Dr. Scott Angle

Celebrating 500 episodes of Talking Biotech, Kevin Folta interviews Dr. Scott Angle, University of Florida Senior Vice President for Agriculture and Natural Resources, to explore the future of agriculture, AI innovations, and Florida's agricultural landscape. Discover insights on technology, workforce development, and sustainable farming practices.

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Biotech Mold Detection and Health - Brian Karr

In this episode of Talking Biotech, we explore cutting-edge biotech tools that are transforming how we detect and address indoor environmental health issues, particularly mold and microbes. With new, highly sensitive methods, we're moving beyond traditional inspection techniques to more precise, source-level detection—crucial for health outcomes.

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Dr. Neil Stewart-Radiation Sensing Potatoes

Plants can't get up and walk away from stress or predators, so they've evolved sensitive systems to sense and in some cases anticipate changes in their environment. Now, there's sensors to light, to humidity, to touch, to gravity, to dozens of other prevailing factors that push information from the external environment into the nucleus, shaping gene expression and adapting. To that change. Now,…

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Milk Proteins without the Dairy - Adam Tarshis and Dr. Cory Tobin

The proteins that give cheese its unique elasticity and eating quality are challenging to create outside of the cow. However, the team at Mozza has developed a method to generate the milk proteins in soybeans, exploiting the potential massive scale of field crop production, and providing a dairy-free source of these important proteins. Today's podcast interviews Adam Tarshis and Dr. Cory Tobin…

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New Technology in Severe Burn Care - Dr. Katie Bush

Severe burns require specialized care and long healing times at great expense. This week's Talking Biotech podcast explores the latest advancements in burn treatment technology with Dr. Katie Bush from Aveda Medical. Discover how innovative cell therapies and regenerative techniques are transforming wound healing, reducing hospital stays, and improving cosmetic outcomes. 00:00 Introduction to Burn…

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Molecular Residue Cancer Detection - Dr. Nate Montgomery

This episode explores the latest advancements in personalized DNA and RNA technologies for early cancer detection, diagnostics, and treatment monitoring. New technologies identify molecular signatures of tumors that help predict onset and re-occurrence of disease. Dr. Nathan Montgomery from Neo Genomics Laboratories discusses how molecular residual disease testing, liquid biopsies, and genomic…

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Strategies in Combating Chronic Kidney Disease - Dr. Salvatore Viscomi

Chronic kidney disease (CKD) is a pressing health issue that affects over a billion people worldwide, yet it often goes unnoticed until it's too late. In this post, we'll explore insights from Dr. Salvatore Viscomi, the CEO and founder of Carna Health, who sheds light on the alarming prevalence of CKD, its underlying causes, and the innovative solutions being implemented to address this global…

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AI and the Future of Healthcare -- Dr. Emilia Javorsky

This week's Talking Biotech Podcast examines the realistic potential of AI in cancer research and healthcare, emphasizing data quality, individualization, and system reform. Guest: Dr. Emilia Javorsky, Future of Life Institute. Future of Life Institute AI and Cancer: A New Frontier

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The First Environmental GE Organism Release - almost! Dr. Steven Lindow

This episode explores the pioneering work on ice minus bacteria and their role in frost damage prevention in plants. Dr. Steven Lindow shares insights into early biotech innovations, regulatory challenges, and the potential for modern applications of this technology.

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New Frontiers in Therapeutic Peptides - Dr. Karsten Eastman

In this episode of the Talking Biotech podcast, Dr. Karsten Eastman discusses the significance of peptides in biology and their therapeutic potential. He explains the roles of peptides, particularly GLP-1 therapeutics, and the challenges associated with their stability and bioavailability. The conversation delves into nature's strategies for enhancing peptide stability and how Sathera Therapeutics…

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Genetic Variation in Vegetative Propagation - Dr. Danelle Seymour

In this episode of the Talking Biotech podcast, Dr. Danelle Seymour discusses the genetic anomoliies observed in the vegetative propagation of tree crops, particularly citrus. The conversation delves into the importance of preserving genetic material through grafting, the challenges of genetic variation in vegetatively propagated plants, and the role of mutations in these processes. Dr. Seymour…

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Conditionally Active Therapeutics - Dr. Neela Patel, Dr. Diane Hollenbaugh

In this episode of the Talking Biotech podcast, Dr. Kevin Folta speaks with Dr. Neela Patel and Dr. Diane Hollenbaugh from Bonum Therapeutics about the emerging field of conditionally active biologics. They discuss the challenges of current therapies, the innovative mechanisms behind their drug development, and the potential of immuno-oncology to revolutionize cancer treatment. The conversation…

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A Plasmid-Based Cancer Therapy - Dr. Alexander Schneider

In this episode of the Talking Biotech podcast, host Dr. Kevin Folta engages with Dr. Alex Schneider, CEO and founder of CureLab, to discuss innovative approaches to cancer treatment, particularly focusing on the challenges posed by refractory cancers such as triple-negative breast cancer and platinum-resistant ovarian cancer. Dr. Schneider emphasizes the evolution of cancer therapies from…

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Biotech in Beauty Products - Nicholas Brideau

This conversation explores the intersection of biotechnology and the beauty industry, highlighting how biotech is revolutionizing the production of cosmetic ingredients. The discussion covers the slow pace of innovation in beauty, the debate between natural and synthetic ingredients, and the role of AI in discovering new active compounds. The conversation also delves into specific examples like…

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Molecular Biology Giants that Left Us In 2025

2025 saw some of the giants in molecular biology leave us. Those that made seminal discoveries in DNA science to those that put it to work in describing the underpinnings of life left an indelible mark on history, and it is fitting that we commemorate their discoveries and contributions.

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TB Throwback- Correcting the Veritasium Episode on Glyphosate

This is a throwback to episode 484, a very important correction of their episode on glyphosate. With so much controversy around this compound it is critical to keep the information correct and consistent with a 50 year body of evidence when discussing risk and benefit. Veritassium made some mistakes, so here they are corrected so that you can participate effectively in these discussions.

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TB Throwback: Gliblastoma and Cindy's Gift

This episode originally aired on December 18, 2021. Cindy Graham was diagnosed with glioblastoma in her late 40s. She fought the disease, and ultimately donated her tissues to research to study the nature of glioblastoma and identify potential vulnerabilities that could underlie a cure. This episode first features Dr. Shiela Singh, glioblastoma expert who has performed analysis of Cindy's cells in…

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TB Throwback: Dr. Avindra Nath and HERV-based Diseases

In today's throwback to 2022, Dr. Avindra Nath of the NIH reviews research efforts in proteins expressed from human endogenous retroviruses. It is a fascinating discussion of how genome relics may be contributing to insidious human disease.

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482 Dr. Maxine Thompson, Episode 117, Jan 18, 2015

This throwback episode to 2018 is an interview with plant breeding pioneer Dr. Maxine Thompson.

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A Biotech Probiotic to Enhance Fiber - Dr. Zack Abbott

In this episode of the Talking Biotech podcast, Dr. Kevin Folta and Dr. Zack Abbott discuss the critical role of dietary fiber in human health, the alarming statistics regarding fiber deficiency in the population, and the innovative solutions being developed by Zbiotics to address this issue. They delve into the science behind genetically engineered probiotics that can convert sugars into fiber,…

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Peer Review and Rigor in Controversial Science - Cam English, Dr. Liza Lockwood

This cross-platform podcast is shared on Science Facts and Fallacies as well as Talking Biotech. Cameron English, Dr. Liza Lockwood and Dr. Kevin Folta discuss the comments made during a rant on the Science Facts and Fallacies podcast concerning the rigor of peer review and alledged lack of self policing in academic publishing. They discuss several papers in the recent public eye, with an emphasis…

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Everyone Else is Lying to You - Pandemic Disinformation - Dr. Jonathan Howard

In this episode of the Talking Biotech podcast, Dr. Jonathan Howard discusses his experiences during the COVID-19 pandemic, the rise of disinformation, and the anti-vaccine movement. He reflects on his role as a physician at Bellevue Hospital, the impact of misinformation on public health, and the key players who have influenced the narrative surrounding vaccines and COVID-19. Dr. Howard…

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Targeting RNA with Therapeutics - Dr. Matthew Disney

Summary In this episode of the Talking Biotech Podcast, Dr. Matthew Disney discusses the potential of RNA as a therapeutic target, exploring its historical context, pathogenic roles in diseases, and the challenges and innovations in drug design. The conversation delves into specific diseases like myotonic dystrophy, ALS, and various cancers, highlighting the advantages of small molecules in…

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Biotech Takes On the Screw Worm - Dr. Max Scott

In this episode of the Talking Biotech podcast, Dr. Max Scott discusses the significant threat posed by screw worms, a parasitic insect that lays eggs in live animals, leading to severe economic and health impacts on livestock. The conversation covers the historical eradication efforts using the sterile insect technique, the current resurgence of screw worms in North America, and the innovative…

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Attacking Cancers through Neoantigens - Dr. Jackie Douglass

In this episode of the Talking Biotech podcast, Dr. Jackie Douglas discusses the emerging field of neoantigens and their significance in cancer immunotherapy. Neoantigens, which are unique to cancer cells, offer a promising target for personalized immunotherapies. The conversation covers the formation of neoantigens, the role of HLA alleles in their presentation, recent advances in research, and…

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Drug Discovery in the Synapse - Derek Small

In this episode of the Talking Biotech podcast, Dr. Kevin Folta interviews Derek Small, co-founder and CEO of Syndeoo, focusing on the increasing prevalence of neurological disorders and the challenges in developing effective therapies. They discuss the importance of synaptic function in mental health and neurodegenerative diseases, the innovative Boost platform for drug development, and the…

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Correcting the Veratasium Glyphosate - Monsanto Episode

Listener Request! The YouTube channel Veritasium has been recognized by scientists and the public as a great source for scientific information. So what happened in the recent episode? The episode originally entitled "Exposing the Monsanto Conspiracy" attempts to link the historic horrors of Agent Orange and contaminated herbicides with current claims against the herbicide glyphosate. To build the…

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Unintended Effects of HPV and Shingles Vaccines - Dr. Kevin Folta

Anti-vaccination activists, including the US Health and Human Services Secretary, decry the risk of vaccination. In two recently developed vaccines the emerging story is that there is risk in not being vaccinated. Analysis of large data sets shows that over the last 20 years, those vaccinated with the HPV vaccine have a lower incidence of cervical, penile and anal cancers, as they should. But they…

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Revolutionizing Agriculture with RNA Technology - Dr. Andrey Zarur

In this episode of the Talking Biotech podcast, Dr. Andrey Zarur, CEO of Greenlight Biosciences, discusses the innovative applications of RNA technology in agriculture. The conversation covers the challenges of food security, the role of RNA in pest control, and the regulatory advantages of RNA-based products. Dr. Zarur highlights the efficacy and safety of RNA insecticides, fungicides, and…

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Glyphosate 10 Years After IARC - Dr. Robert Tarone

Summary In this episode of the Talking Biotech podcast, Dr. Kevin Folta interviews Dr. Robert Tarone, a retired scientist with extensive experience in cancer statistics and experimental design. They discuss the controversial IARC monograph that classified glyphosate as a probable human carcinogen, the flaws in the evaluation process, and the implications of this classification on legal actions…

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Glyphosate: 10 Lessons from 10 Years After IARC - Dr. David Zaruk

In this episode of the Talking Biotech podcast, Kevin Folta and Dr. David Zaruk discuss the complexities surrounding glyphosate, particularly in light of the IARC Monograph 112 published a decade ago. They explore the implications of the reclassification of glyphosate as a probable carcinogen, the ensuing litigation, influence and corruption, and the ethical concerns regarding scientific…

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Evidence of Pig Domestication - Dr. Jiajing Wang

This conversation explores the domestication of pigs, highlighting their importance in human society, the historical evidence of their domestication, and innovative research methods used to study their relationship with humans. Dr. Jiajing Wang from Dartmouth College discusses the significance of dental calculus in elucidaing pig diets and behaviors, as well as the complex interactions between…

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The Shingles Vaccines and Dementia - Dr. Pascal Geldsetzer

In this episode of the Talking Biotech podcast, Dr. Kevin Folta speaks with Dr. Pascal Geldsetzer about the relationship between the shingles vaccine and dementia. They discuss the prevalence of shingles, the current vaccination rates, and the potential implications of shingles vaccination on cognitive decline. The data come from a clever analysis of public health data that revealed this…

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Old Tricks, New Wheat for Celiacs - Maria Rottersman

Summary In this episode of the Talking Biotech Podcast, Kevin Folta speaks with Maria Rodtersman, a Ph.D. candidate at UC Davis, about her research on developing wheat to reduce gluten content, specifically targeting immunogenic proteins that trigger celiac disease. They discuss the significance of wheat as a staple crop, the differences between celiac disease and gluten sensitivity, and the use…

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A Tribute to Dr. Franklin Stahl and His Elegant Experiment

The elucidation of DNA's structure led to questions about how it was replicated. Today's Talking Biotech Podcast commemorates the landmark experiments by Dr. Franklin Stahl, who died recently at the age of 95. The experiments have beed described as amont the most elegant in the history of biology, and used a simple test to determine the physical nature of DNA replication. This is a must-know story…

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Social Media, Traditional Media, Ag Misinformation - Connie Diekman and Dr. Cami Ryan

In this episode of the Talking Biotech Podcast, Dr. Kevin Folta discusses the challenges of misinformation in food science with Dr. Cami Ryan and registered dietitian Connie Diekman. They explore the role of social media and traditional media in spreading misinformation, the difficulties scientists face in communicating effectively, and the importance of peer review and other information-honing…

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We Are Eating the Earth - Michael Grunwald

In this episode of the Talking Biotech Podcast (464) host Dr. Kevin Folta engages with journalist and author Michael Grunwald about his book 'We Are Eating the Earth.' They discuss the complex relationship between food production, climate change, and biotechnology, emphasizing the need for multifaceted solutions rather than single silver bullet approaches. Grunwald shares insights from his journey…

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New Solutions for Anorexia Nervosa and Obesity - Dr. Roger Cone

In this episode of the Talking Biotech podcast, Dr. Roger Cone discusses the complexities of obesity and eating disorders, emphasizing the role of brain circuits in regulating feeding behaviors. He explains the significance of GLP-1 agonists and melanocortin receptors in developing therapeutic approaches for conditions like obesity, anorexia, and cachexia. The conversation highlights the potential…

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Brainstorming to Defeat Antimicrobial Resistance - Dr. Anita Shukla

This episode of the Talking Biotech podcast features Dr. Anita Shukla discussing the critical issue of antibiotic resistance and the innovative engineering solutions being explored to combat it. The conversation covers the evolutionary nature of antimicrobial resistance (AMR), the importance of antibiotics in healthcare, and the collaborative efforts of the Engineering Research Visioning Alliance…

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A Grassroots Run for Ag Commissioner - Dr. Sarah Taber

In this episode of the Talking Biotech podcast, Dr. Kevin Folta interviews Dr. Sarah Taber, who shares her journey from agricultural consulting to running for Ag Secretary in North Carolina. It is mostly a story of dedication to changing the norms and changing the rules to benefit more farmers, trying to break deeply entrenched interests to create real change. The conversation explores the…

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Where Did The Bird Flu Go? - Dr. Kevin Folta

In this episode of the Talking Biotech podcast, Dr. Kevin Folta discusses the current state of avian influenza, particularly the H5N1 strain, its history, zoonotic potential, and the implications for both poultry and human health. Into 2025 it was being detected in wild birds,domestic flocks, cattle and humans. Where did it go? He highlights the importance of surveillance, the impact of the virus…

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The Origin of Critical Maize Traits - Regina Fairbanks and Dr. Jeffrey Ross-Ibarra

This episode of the Talking Biotech podcast delves into the evolutionary significance and domestication history of corn (maize). Dr. Kevin Folta hosts a discussion with Regina Fairbanks and Dr. Jeffrey Ross-Ibarra from UC Davis, exploring the traits that enabled maize's domestication, the role of the TGA gene, and the implications for modern breeding. The conversation highlights the importance of…

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The GE Corn Ban in Mexico - Luis Ventura

In this episode of the Talking Biotech podcast, Kevin Folta and Luis Ventura discuss the recent constitutional ban on genetically engineered corn in Mexico. They explore the implications of this regulation, the disinformation surrounding it, and the challenges faced by Mexican farmers. The conversation also touches on the broader impact of this ban on biotechnology in Latin America and the…

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The Mexico GMO Corn Controversy - Luis Ventura

This conversation explores the complex relationship between corn and Mexico, focusing on its cultural, economic, and agricultural significance. The discussion highlights the moratorium on genetically engineered (GM; GMO) corn, the public perception of biotechnology, and the impact of environmental NGOs on policy decisions. The conversation also delves into the perspectives of farmers regarding the…

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Synthetic Biology and Natural Products - Dr. Philipp Zerbe

This conversation explores the intersection of natural products and synthetic biology, emphasizing the importance of science communication and outreach. Julia Ball shares her passion for connecting the public with plant science, while Dr. Philip Zerbe discusses the potential of synthetic biology in producing valuable natural products, particularly terpenoids. The discussion highlights the…

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