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Dave Asprey's Substack · Aug 19, 2026

Rapamycin Has Nasty Side Effects. Here’s How I Activate Cellular Cleanup Without It.

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Dave Asprey · Dave Asprey's Substack

I tried rapamycin about eight years ago, before it became mainstream. I took it long enough to know how it felt in my body.

I just didn't feel good on it. And I'm not really looking to do things that make me feel bad. So I stopped.

Since then rapamycin has become the most talked-about longevity drug on earth. Clinics prescribe it off-label and podcasters take it weekly. What you don’t hear about often are the side effects. Is there a way to get the benefits without actually taking rapamycin?

In the full version you’ll get:

  • How rapamycin works

  • Side effects of rapamycin

  • The six things you can do to get the benefits without the downsides

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Read the original on substack.daveasprey.com

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